Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25852110 | 0.84 | HRH3 (0.36) | RECQLPOLBTSHR | |
| SCHEMBL25850243 | 0.83 | HRH3 (0.38) | RECQLAKR1C3MEN1KMT2A | |
| SCHEMBL25849000 | 0.81 | PDK1 (0.41) | RECQLALDH1A1 | |
| SCHEMBL25851585 | 0.78 | NPSR1 (0.41) | MEN1KMT2ATSHRLMNAALDH1A1 | |
| SCHEMBL25853513 | 0.77 | — | — | |
| SCHEMBL25853617 | 0.76 | CHRM1 (0.35) | RECQL | |
| SCHEMBL25849855 | 0.73 | GRM5 (0.41) | POLBKMT2AMAPTHTT | |
| SCHEMBL25848587 | 0.72 | RIPK1 (0.35) | — | |
| SCHEMBL17888270 | 0.70 | AKR1C3 (0.50) | RECQLAKR1C3MEN1TP53KMT2A | |
| SCHEMBL2899860 | 0.70 | MEN1 (0.80) | RECQLPOLBAKR1C3MEN1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131122-A1 | FUSED RING-SUBSTITUTED SIX-MEMBERED HETEROCYCLIC COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 劲方医药科技(上海)有限公司 | 2023-07-13 | — | — | WO | disclosed |