SCHEMBL25850028

SCHEMBL25850028

Cc1ccc2c(c1)C(=O)/C(=C\c1ccc3c(c1)C(C)(C)c1cc(C(C)C)ccc1N3c1ccccc1)C2=O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CSNK2A2 P19784 2/20 0.42
CSNK2B P67870 2/20 0.42
CSNK2A1 P68400 2/20 0.42
CSNK2A3 Q8NEV1 2/20 0.42
KMT2A Q03164 8/20 0.37
MEN1 O00255 7/20 0.37
GAA P10253 2/20 0.37
ALDH1A1 P00352 8/20 0.36
MAPT P10636 6/20 0.36
KDM4E B2RXH2 5/20 0.36
ELANE P08246 1/20 0.35
EGLN1 Q9GZT9 1/20 0.35
NPSR1 Q6W5P4 2/20 0.34
HSD17B10 Q99714 1/20 0.34
EGFR P00533 1/20 0.34
ERBB2 P04626 1/20 0.34
IGF1R P08069 1/20 0.34
PDGFRB P09619 1/20 0.34
GLB1 P16278 1/20 0.34
CTRC Q99895 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25850024 0.92 CSNK2A2 (0.43) CSNK2A2CSNK2BCSNK2A1CSNK2A3KMT2A
SCHEMBL25849960 0.91 CSNK2A2 (0.42) CSNK2A2CSNK2BCSNK2A1CSNK2A3KMT2A
SCHEMBL25851481 0.90 CSNK2A2 (0.41) CSNK2A2CSNK2BCSNK2A1CSNK2A3KMT2A
SCHEMBL25850026 0.90 CSNK2A2 (0.39) CSNK2A2CSNK2BCSNK2A1CSNK2A3KMT2A
SCHEMBL25850003 0.87 CSNK2A2 (0.39) CSNK2A2CSNK2BCSNK2A1CSNK2A3KMT2A
SCHEMBL25850011 0.86 MEN1 (0.36) CSNK2A2CSNK2BCSNK2A1CSNK2A3KMT2A
SCHEMBL25851462 0.85 CSNK2A2 (0.39) CSNK2A2CSNK2BCSNK2A1CSNK2A3KMT2A
SCHEMBL25850029 0.85 ALDH1A1 (0.34) CSNK2A2CSNK2BCSNK2A1CSNK2A3KMT2A
SCHEMBL25850008 0.85 CSNK2A2 (0.38) CSNK2A2CSNK2BCSNK2A1CSNK2A3KMT2A
SCHEMBL25850014 0.84 MEN1 (0.37) CSNK2A2CSNK2BCSNK2A1CSNK2A3KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230232713-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, AND COMPOUND FUJIFILM CORPORATION (JP) 2023-07-20 US disclosed