SCHEMBL25850025

SCHEMBL25850025

Cc1ccc2c(c1)C(=O)/C(=C/c1cc3c(s1)N(c1ccccc1)c1ccc(C)cc1C3(C)C)C2=O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 9/20 0.38
MAPT P10636 9/20 0.38
ALDH1A1 P00352 8/20 0.38
MEN1 O00255 8/20 0.38
NPSR1 Q6W5P4 3/20 0.38
NPC1 O15118 1/20 0.38
CRHBP P24387 1/20 0.38
RAB9A P51151 1/20 0.38
CRHR2 Q13324 1/20 0.38
TDP1 Q9NUW8 3/20 0.37
HPGD P15428 2/20 0.37
THRB P10828 1/20 0.37
RECQL P46063 1/20 0.37
ELANE P08246 1/20 0.36
KDM4E B2RXH2 4/20 0.35
LMNA P02545 4/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
HSD17B10 Q99714 1/20 0.35
MITF O75030 1/20 0.35
PLA2G1B P04054 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25849962 0.95 KMT2A (0.38) KMT2AMAPTALDH1A1MEN1NPSR1
SCHEMBL25851466 0.93 ALDH1A1 (0.35) KMT2AMAPTALDH1A1MEN1NPSR1
SCHEMBL25850000 0.93 PGR (0.35) KMT2AMAPTALDH1A1MEN1NPSR1
SCHEMBL25850029 0.93 ALDH1A1 (0.34) KMT2AMAPTALDH1A1MEN1NPSR1
SCHEMBL25850006 0.91 ALDH1A1 (0.33) KMT2AMAPTALDH1A1MEN1NPSR1
SCHEMBL25850015 0.90 ALDH1A1 (0.35) KMT2AMAPTALDH1A1MEN1NPSR1
SCHEMBL25850020 0.89 ALDH1A1 (0.34) KMT2AMAPTALDH1A1MEN1NPSR1
SCHEMBL25850009 0.88 MAPT (0.33) KMT2AMAPTALDH1A1MEN1NPSR1
SCHEMBL23695458 0.87 ALDH1A1 (0.41) KMT2AMAPTALDH1A1MEN1NPSR1
SCHEMBL25849976 0.87 KMT2A (0.38) KMT2AMAPTALDH1A1MEN1NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230232713-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, AND COMPOUND FUJIFILM CORPORATION (JP) 2023-07-20 US disclosed