SCHEMBL25850039

SCHEMBL25850039

Cc1ccc2c(c1)C(=O)/C(=C/C=C1\Sc3ccccc3N1C)C2=O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.45
ALDH1A1 P00352 9/20 0.43
MAPT P10636 8/20 0.43
HPGD P15428 1/20 0.43
KMT2A Q03164 5/20 0.41
MEN1 O00255 4/20 0.41
HSD17B10 Q99714 2/20 0.41
MAOA P21397 2/20 0.41
NPC1 O15118 12/20 0.40
RAB9A P51151 12/20 0.40
L3MBTL1 Q9Y468 4/20 0.40
KDM4E B2RXH2 3/20 0.40
GFER P55789 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
SMN1; SMN2 Q16637 5/20 0.40
NFKB1 P19838 3/20 0.40
NFKB2 Q00653 3/20 0.40
RELA Q04206 3/20 0.40
TP53 P04637 3/20 0.40
TDP1 Q9NUW8 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25851505 0.86 ALDH1A1 (0.42) ALDH1A1MAPTHPGDKMT2AMEN1
SCHEMBL25849797 0.86 ALDH1A1 (0.46) ALDH1A1MAPTHPGDKMT2AMEN1
SCHEMBL15726368 0.81 ALDH1A1 (0.44) ALDH1A1MAPTHPGDKMT2AMEN1
SCHEMBL14435900 0.80 ALDH1A1 (0.48) ALDH1A1MAPTHPGDKMT2AMEN1
SCHEMBL25850041 0.79 DRD3 (0.41) ELANEALDH1A1MAPTKMT2AMEN1
SCHEMBL13445655 0.77 ALDH1A1 (0.50) ALDH1A1MAPTHPGDKMT2AMEN1
SCHEMBL25849804 0.75 MAPT (0.41) ALDH1A1MAPTHPGDKMT2AMEN1
SCHEMBL25850036 0.72 MAPT (0.64) ELANEALDH1A1MAPTKMT2AMEN1
SCHEMBL10621154 0.72 ALDH1A1 (0.57) ALDH1A1MAPTHPGDKMT2AMEN1
SCHEMBL10621158 0.72 ALDH1A1 (0.57) ALDH1A1MAPTHPGDKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230232713-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, AND COMPOUND FUJIFILM CORPORATION (JP) 2023-07-20 US disclosed