SCHEMBL25850041

SCHEMBL25850041

Cc1ccc2c(c1)C(=O)/C(=C/C=C1\Sc3c(ccc4ccccc34)N1C)C2=O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DRD3 P35462 2/20 0.41
ELANE P08246 1/20 0.40
NTRK1 P04629 1/20 0.37
TDO2 P48775 1/20 0.37
IDO2 Q6ZQW0 1/20 0.37
MAPT P10636 5/20 0.36
RAB9A P51151 2/20 0.36
KMT2A Q03164 2/20 0.36
MEN1 O00255 1/20 0.36
NPC1 O15118 1/20 0.36
GAA P10253 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
NOX1 Q9Y5S8 1/20 0.36
MAOA P21397 1/20 0.35
MAOB P27338 1/20 0.35
DNMT1 P26358 1/20 0.35
LCK P06239 1/20 0.33
IDO1 P14902 1/20 0.33
PRMT1 Q99873 2/20 0.32
KDM4E B2RXH2 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25849799 0.90 DRD3 (0.35) DRD3MAPTRAB9AKMT2AMEN1
SCHEMBL25851513 0.88 DNMT1 (0.34) DRD3DNMT1PRMT1
SCHEMBL25850039 0.79 ELANE (0.45) ELANEMAPTRAB9AKMT2AMEN1
SCHEMBL25849806 0.79 ALDH1A1 (0.33) MAPTKMT2AMEN1DNMT1PRMT1
SCHEMBL25850040 0.75 MEN1 (0.43) ELANENTRK1TDO2IDO2MAPT
SCHEMBL9908061 0.72 MAOA (0.40) ELANEMAPTRAB9AKMT2AMEN1
SCHEMBL25849797 0.70 ALDH1A1 (0.46) DRD3MAPTRAB9AKMT2AMEN1
SCHEMBL12776610 0.68 DRD3 (0.48) DRD3MAPTRAB9AKMT2AMEN1
SCHEMBL25851505 0.67 ALDH1A1 (0.42) DRD3MAPTRAB9AKMT2AMEN1
SCHEMBL10843290 0.66 RAB9A (0.47) MAPTRAB9AKMT2AMEN1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230232713-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, AND COMPOUND FUJIFILM CORPORATION (JP) 2023-07-20 US disclosed