Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | ACHE | P22303 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA7 | P43166 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.35 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL15845273 | 0.97 | TSHR (0.45) | TSHRACHEALDH1A1CA1CA2 | |
| SCHEMBL541710 | 0.83 | TSHR (0.47) | TSHRACHEALDH1A1CA1CA2 | |
| SCHEMBL31258279 | 0.83 | TSHR (0.47) | TSHRACHEALDH1A1CA1CA2 | |
| SCHEMBL10912630 | 0.79 | TRPA1 (0.42) | TSHRACHEALDH1A1CA1CA2 | |
| SCHEMBL9326405 | 0.79 | TSHR (0.43) | TSHRACHEALDH1A1CA1CA2 | |
| SCHEMBL15871414 | 0.79 | CYP2A6 (0.38) | TSHRACHEALDH1A1CA1CA2 | |
| SCHEMBL1176479 | 0.79 | TSHR (0.43) | TSHRACHEALDH1A1CA1CA2 | |
| SCHEMBL1986740 | 0.78 | TSHR (0.35) | TSHRCYP3A4TDP1CYP1A2CYP2A6 | |
| SCHEMBL30391714 | 0.78 | TSHR (0.35) | TSHRCYP3A4TDP1CYP1A2CYP2A6 | |
| SCHEMBL8647690 | 0.78 | TSHR (0.47) | TSHRACHEALDH1A1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1354886-B1 | Process for the preparation of tertiary phosphines | SALTIGO GMBH (DE) | 2009-08-26 | — | — | EP | claimed |
| US-7230136-B2 | Reacting phosphorus halide with organomagnesium compound in presence of copper compound | LANXESS DEUTSCHLAND GMBH (DE) | 2007-06-12 | — | — | US | claimed |
| US-20030229240-A1 | Reacting phosphorus halide with organomagnesium compound in presence of copper compound | LANXESS DEUTSCHLAND GMBH (DE) | 2003-12-11 | — | — | US | claimed |
| EP-1354886-A1 | Process for the preparation of tertiary phosphines | Bayer Aktiengesellschaft (DE) | 2003-10-22 | — | — | EP | claimed |
| CN-112480169-A | Liquid phosphorus-containing compound and application and preparation method thereof | 南雄志一精细化工有限公司 | 2021-03-12 | — | — | CN | disclosed |
| CN-104447859-A | Synthesis process of phosphinate containing alkylaryl | NANJING JINYUAN FLAME RETARDANT TECHNOLOGY CO LTD | 2015-03-25 | — | — | CN | disclosed |
| WO-2014108487-A1 | P-STEREOGENIC CHIRAL PRECURSOR OF CHIRAL LIGANDS AND USE THEREOF | UNIVERSITE D'AIX-MARSEILLE (FR) | 2014-07-17 | — | — | WO | disclosed |
| WO-2014108487-A1 | P-STEREOGENIC CHIRAL PRECURSOR OF CHIRAL LIGANDS AND USE THEREOF | UNIVERSITE D'AIX-MARSEILLE (FR) | 2014-07-17 | — | — | WO | disclosed |
| CN-101490065-B | Method for producing organic phosphorous compounds containing halogene | BASF SE | 2013-06-19 | — | — | CN | disclosed |
| US-8067642-B2 | Chiral phosphorous compounds | Celtice Catalysts Limited, Nova UCD (IE) | 2011-11-29 | — | — | US | disclosed |
| EP-2044092-B1 | METHOD FOR PRODUCING ORGANIC PHOSPHOROUS COMPOUNDS CONTAINING HALOGENE | BASF SE (DE) | 2011-09-28 | — | — | EP | disclosed |
| US-7847126-B2 | prepared by reacting phosphorus halide with organomagnesium compound in presence of copper compound; di(tert-butyl)phenylphosphonium tetrafluoroborate, for example | LANXESS DEUTSCHLAND GMBH (DE) | 2010-12-07 | — | — | US | disclosed |
| EP-0122587-B1 | PROCESS FOR PREPARING ORGANIC CHLOROPHOSPHANES | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-04-20 | — | — | EP | disclosed |
| US-4632995-A | Process for the preparation of phenyl- and thienyl-chlorophosphane derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-12-30 | — | — | US | disclosed |
| US-4536351-A | ADDING AN ALKALI CHLORIDE AS COMPLEXING AGENT; BY-PRODUCT INHIBITION | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-08-20 | — | — | US | disclosed |
| US-4535144-A | AMINOARYL ESTER REACTANT, TWO-STAGE MELT POLYMERIZATION | CELANESE CORPORATION (US) | 1985-08-13 | — | — | US | disclosed |
| US-4533725-A | BY-PRODUCT INHIBITION; HEATING A FOAMED PREPOLYMER | DELANESE CORPORATION (US) | 1985-08-06 | — | — | US | disclosed |
| EP-0122587-A2 | Process for preparing organic chlorophosphanes | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-10-24 | — | — | EP | disclosed |
| EP-0024128-B1 | PHOSPHORYLATION PROCESS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-02-01 | — | — | EP | disclosed |
| EP-0024128-A2 | Phosphorylation process | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1981-02-25 | — | — | EP | disclosed |