SCHEMBL1986740

SCHEMBL1986740

ClP(Cl)c1ccccc1P(Cl)Cl

nearest known ligand 0.35

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.35
LMNA P02545 1/20 0.35
CYP3A4 P08684 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
CYP2A6 P11509 2/20 0.31
ALOX12 P18054 1/20 0.31
CYP1A2 P05177 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30391714 1.00 TSHR (0.35) TSHRLMNACYP3A4TDP1CYP2A6
SCHEMBL7602941 0.81 TSHR (0.50) TSHRLMNACYP2A6CYP1A2
SCHEMBL10706514 0.81 TSHR (0.50) TSHRLMNACYP2A6CYP1A2
SCHEMBL1041344 0.78 ACHE (0.38)
SCHEMBL31536312 0.78 ALDH1A1 (0.38) TDP1
SCHEMBL258502 0.78 TSHR (0.47) TSHRLMNACYP3A4TDP1CYP2A6
Hydrochloric Acid SCHEMBL15845273 0.76 TSHR (0.45) TSHRLMNACYP3A4TDP1CYP2A6
SCHEMBL2879307 0.74 CYP2A6 (0.48) TDP1CYP2A6CYP1A2
SCHEMBL2368837 0.74 CYP1A2 (0.48) TSHRCYP3A4TDP1CYP2A6CYP1A2
SCHEMBL3937434 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1598053-B1 Use of a composition containing at least one phosphine as majority reducing agent to remove the artificial colour of keratinic fibres OREAL (FR) 2006-12-20 EP claimed
EP-1598053-A1 Use of a composition containing at least one phosphine as majority reducing agent to remove the artificial colour of keratinic fibres L'OREAL (FR) 2005-11-23 EP claimed
US-20050251928-A1 Method for stripping artificial color from keratin fibers L'OREAL (FR) 2005-11-17 US claimed
US-12291489-B2 Synthesis of nanocomposites and their use in enhancing plant nutrition WASHINGTON UNIVERSITY (US) 2025-05-06 US disclosed
US-20230165771-A1 PROCESS FOR TREATING KERATIN FIBERS USING PARTICULAR AMINO ACIDS IN HIGH CONCENTRATION L'OREAL (FR) 2023-06-01 US disclosed
US-20220176363-A1 PROCESS FOR OLIGOMERIZATION DOW GLOBAL TECHNOLOGIES LLC (US) 2022-06-09 US disclosed
US-20210129125-A1 PROCESS FOR OLIGOMERIZATION DOW GLOBAL TECHNOLOGIES LLC (US) 2021-05-06 US disclosed
US-10981156-B2 Chromium complex and catalyst therefrom DOW GLOBAL TECHNOLOGIES LLC (US) 2021-04-20 US disclosed
US-10919031-B2 Process for oligomerization DOW GLOBAL TECHNOLOGIES LLC (US) 2021-02-16 US disclosed
US-20200338542-A1 PROCESS FOR OLIGOMERIZATION DOW GLOBAL TECHNOLOGIES LLC (US) 2020-10-29 US disclosed
US-10702861-B2 Process for oligomerization DOW GLOBAL TECHNOLOGIES LLC (US) 2020-07-07 US disclosed
EP-1593432-A2 Polymer-supported phosphorus ligands for catalysis E.I. du Pont de Nemours and Company (US) 2005-11-09 EP disclosed
EP-1593431-A2 Polymer-supported phosphorus ligands for catalysis E. I. du Pont de Nemours and Company (US) 2005-11-09 EP disclosed
EP-1593430-A2 Polymer-Supported phosphorus ligands for catalysts E.I. DU PONT DE NEMOURS & COMPANY INCORPORATED (US) 2005-11-09 EP disclosed
WO-2005056566-A2 METHOD FOR PRODUCING ORTHOMETALATED AND ORTHOSUBSTITUTED AROMATIC COMPOUNDS SOLVIAS AG (CH) 2005-06-23 WO disclosed
US-20030228629-A1 Polymer-supported phosphorus ligands for catalysts FAGAN PAUL J (US) 2003-12-11 US disclosed
US-6630604-B1 Phosphine and phosphine oxide ligands are prepared using polymeric supports. These compounds can be easily cleaved from the support, and along with the corresponding supported compounds, used as ligands in the preparation of novel, E. I. DU PONT DE NEMOURS AND COMPANY 2003-10-07 US disclosed
US-20030104476-A1 Polymer-supported phosphorus ligands for catalysis FAGAN PAUL J (US) 2003-06-05 US disclosed
EP-1133357-A2 POLYMER-SUPPORTED PHOSPHORUS LIGANDS FOR CATALYSIS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2001-09-19 EP disclosed
WO-2000021663-A2 POLYMER-SUPPORTED PHOSPHORUS LIGANDS FOR CATALYSIS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2000-04-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210129125-A1 PROCESS FOR OLIGOMERIZATION OXER1, NOD1, LIG1 TSHR 4279/4885LMNA 3488/4885CYP3A4 1092/4885
US-20200338542-A1 PROCESS FOR OLIGOMERIZATION OXER1, NOD1, LIG1 TSHR 4279/4885LMNA 3488/4885CYP3A4 1092/4885
US-20030228629-A1 Polymer-supported phosphorus ligands for catalysts PHOSPHO1, PSPH, PNKP TSHR 4266/4885LMNA 2958/4885CYP3A4 4154/4885
US-10919031-B2 Process for oligomerization OXER1, NOD1, LIG1 TSHR 4279/4885LMNA 3488/4885CYP3A4 1092/4885
US-10981156-B2 Chromium complex and catalyst therefrom OXER1, LIG1, PICALM TSHR 4123/4885LMNA 3103/4885CYP3A4 2079/4885
US-20230165771-A1 PROCESS FOR TREATING KERATIN FIBERS USING PARTICULAR AMINO ACIDS IN HIGH CONCENTRATION KRT18, CKAP4, VIM TSHR 4711/4885LMNA 726/4885CYP3A4 4371/4885
US-20220176363-A1 PROCESS FOR OLIGOMERIZATION OXER1, NOD1, LIG1 TSHR 4279/4885LMNA 3488/4885CYP3A4 1092/4885
US-20050251928-A1 Method for stripping artificial color from keratin fibers KRT18, DSG1, JUP TSHR 4245/4885LMNA 1039/4885CYP3A4 4442/4885
US-10702861-B2 Process for oligomerization OXER1, NOD1, LIG1 TSHR 4279/4885LMNA 3488/4885CYP3A4 1092/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.