⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4596140 | 0.98 | TSHR (0.45) | — | |
| SCHEMBL23049686 | 0.84 | TSHR (0.33) | — | |
| SCHEMBL23615766 | 0.84 | PRKCA (0.34) | — | |
| SCHEMBL9705578 | 0.83 | — | — | |
| SCHEMBL27685740 | 0.81 | — | — | |
| Hydrochloric Acid SCHEMBL9018961 | 0.81 | MAPT (0.50) | — | |
| SCHEMBL17962546 | 0.81 | — | — | |
| Ethylenediamine SCHEMBL7702384 | 0.81 | TSHR (0.43) | — | |
| SCHEMBL9493736 | 0.81 | TSHR (0.44) | — | |
| SCHEMBL25747623 | 0.79 | MAPT (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 92 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116380924-A | Penetrating fluid for fluorescent penetration flaw detection and preparation method thereof | 苏州扛把子检测科技有限公司 | 2023-07-04 | — | — | CN | claimed |
| CN-103575813-B | Alvimopan or its have the HPLC (high performance liquid chromatography) of related substance | 北大方正集团有限公司 | 2016-12-21 | — | — | CN | claimed |
| EP-2463279-B1 | 4-(1,2,4-dioxazol-3-yl)benzamides for the treatment of diabetes and obesity | DAIICHI SANKYO CO LTD (JP) | 2014-02-12 | — | — | EP | claimed |
| CN-103575813-A | HPLC analysis method for alvimopan or related compounds of the alvimopan | UNIV PEKING FOUNDER GROUP CO | 2014-02-12 | — | — | CN | claimed |
| US-8557802-B2 | Amide derivative | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2013-10-15 | — | — | US | claimed |
| CN-1888878-B | Non-combustible dye check cleaning liquid and preparation method thereof | HUDONG ZHONGHUA SHIPBUILDING | 2012-05-30 | — | — | CN | claimed |
| US-20120129832-A1 | AMIDE DERIVATIVE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2012-05-24 | — | — | US | claimed |
| JP-4745230-B2 | — | — | 2011-08-10 | — | — | JP | claimed |
| JP-2008500265-A | — | — | 2008-01-10 | — | — | JP | claimed |
| CN-1888876-A | Non-combustion dye check penetrating fluid and preparing method thereof | HUDONG ZHONGHUA SHIPBUILDING (CN) | 2007-01-03 | — | — | CN | claimed |
| CN-1888878-A | Non-combustion dye check cleaning liquid and preparing method thereof | HUDONG ZHONGHUA SHIPBUILDING (CN) | 2007-01-03 | — | — | CN | claimed |
| EP-1646642-A2 | INHIBITORS OF SERINE PROTEASES, PARTICULARLY HCV NS3-NS4A PROTEASE | Vertex Pharmaceuticals Incorporated (US) | 2006-04-19 | — | — | EP | claimed |
| WO-2005007681-A9 | INHIBITORS OF SERINE PROTEASES, PARTICULARLY HCV NS3-NS4A PROTEASE | — | 2006-04-06 | — | — | WO | claimed |
| WO-2005007681-A2 | INHIBITORS OF SERINE PROTEASES, PARTICULARLY HCV NS3-NS4A PROTEASE | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2005-01-27 | — | — | WO | claimed |
| EP-4393937-A1 | STEROID COMPOUND AND CONJUGATE THEREOF | Duality Biologics (Suzhou) Co., Ltd. (CN) | 2024-07-03 | — | — | EP | disclosed |
| US-11771680-B2 | Pyrrole compounds | ALIGOS THERAPEUTICS, INC. (US) | 2023-10-03 | — | — | US | disclosed |
| CN-110204484-B | The method comprises the following steps of 18 F-labeled fluoropyridine formylglycine, and preparation method and application thereof | 山西医科大学第一医院 | 2023-07-21 | — | — | CN | disclosed |
| EP-0657428-A1 | Preparation of 3,4,4-trisubstitutedpiperidinyl-n-alkylcarboxylates and intermediates, useful as opioid antagonists | ELI LILLY AND COMPANY (US) | 1995-06-14 | — | — | EP | disclosed |
| EP-0644191-A1 | PYRIDINE COMPOUND AND MEDICINAL USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1995-03-22 | — | — | EP | disclosed |
| EP-0600092-A1 | THIAZOLE DERIVATIVE | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-06-08 | — | — | EP | disclosed |