SCHEMBL25850983

SCHEMBL25850983

Bc1ccc2c(c1)C(=O)/C(=C/C=C1/N(c3c(C(C)C)cccc3C(C)C)c3nc4cc(C)c(F)cc4nc3N1c1c(C(C)C)cccc1C(C)C)C2=O

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ANPEP P15144 3/20 0.33
DPP4 P27487 3/20 0.33
NR1H2 P55055 1/20 0.30
NR1H3 Q13133 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25850974 0.93 ANPEP (0.36) ANPEPDPP4NR1H2NR1H3
SCHEMBL25850922 0.88 ANPEP (0.37) ANPEPDPP4NR1H2NR1H3
SCHEMBL25849833 0.86 ANPEP (0.36) ANPEPDPP4NR1H2NR1H3
SCHEMBL23338666 0.84 DPP4 (0.36) ANPEPDPP4NR1H2NR1H3
SCHEMBL25849837 0.84 ANPEP (0.37) ANPEPDPP4NR1H2NR1H3
SCHEMBL25850997 0.83 TP53 (0.39) ANPEPDPP4
SCHEMBL23337888 0.83 DPP4 (0.37) ANPEPDPP4NR1H2NR1H3
SCHEMBL25850960 0.81 ANPEP (0.39) ANPEPDPP4NR1H2NR1H3
SCHEMBL23338667 0.81 ANPEP (0.34) ANPEPDPP4NR1H2NR1H3
SCHEMBL25851049 0.80 MEN1 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230232713-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, AND COMPOUND FUJIFILM CORPORATION (JP) 2023-07-20 US disclosed