SCHEMBL25850997

SCHEMBL25850997

Bc1ccc2c(c1)C(=O)/C(=C/C=C1/N(c3c(C(C)C)cccc3C(C)C)c3nc4ccc(OC)cc4nc3N1c1c(C(C)C)cccc1C(C)C)C2=O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.39
KMT2A Q03164 4/20 0.34
MEN1 O00255 3/20 0.34
ALDH1A1 P00352 3/20 0.34
POLB P06746 3/20 0.34
RAB9A P51151 3/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
KDM4E B2RXH2 2/20 0.34
NPC1 O15118 1/20 0.34
LMNA P02545 1/20 0.34
NQO2 P16083 1/20 0.34
LCK P06239 3/20 0.33
PRKACA P17612 1/20 0.33
PRKACG P22612 1/20 0.33
PRKACB P22694 1/20 0.33
ANPEP P15144 2/20 0.33
DPP4 P27487 1/20 0.33
MAPT P10636 4/20 0.32
TDP1 Q9NUW8 2/20 0.32
MAPK1 P28482 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23337885 0.91 TP53 (0.44) TP53KMT2AMEN1ALDH1A1POLB
SCHEMBL25849838 0.90 TP53 (0.40) TP53KMT2AMEN1ALDH1A1POLB
SCHEMBL25850922 0.89 ANPEP (0.37) KMT2AMEN1ANPEPDPP4MAPT
SCHEMBL25850974 0.87 ANPEP (0.36) ANPEPDPP4
SCHEMBL25849598 0.86 TP53 (0.41) TP53KMT2AMEN1ALDH1A1POLB
SCHEMBL23337594 0.84 TP53 (0.38) TP53KMT2AMEN1ALDH1A1POLB
SCHEMBL25850983 0.83 ANPEP (0.33) ANPEPDPP4
SCHEMBL25850960 0.81 ANPEP (0.39) ANPEPDPP4
SCHEMBL23337591 0.81 DPP4 (0.39) KMT2AMEN1ALDH1A1RAB9AKDM4E
SCHEMBL23337546 0.80 DPP4 (0.42) TP53KMT2AMEN1ALDH1A1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230232713-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, AND COMPOUND FUJIFILM CORPORATION (JP) 2023-07-20 US disclosed