SCHEMBL25852136

SCHEMBL25852136

c1ccc(-c2cccc3oc4cc(-n5c6ccccc6c6cc(-c7ccc8c(c7)c7ccccc7n8-c7ccccc7)ccc65)ccc4c23)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.41
KDM4E B2RXH2 1/20 0.41
ATM Q13315 1/20 0.41
KMT2A Q03164 3/20 0.33
PTGER4 P35408 2/20 0.33
MEN1 O00255 2/20 0.33
ALDH1A1 P00352 2/20 0.33
POLB P06746 1/20 0.33
TSHR P16473 1/20 0.33
BRCA1 P38398 1/20 0.33
HSD17B10 Q99714 1/20 0.33
EDNRB P24530 1/20 0.32
EDNRA P25101 1/20 0.32
PLA2G2A P14555 2/20 0.32
PLA2G4A P47712 2/20 0.32
MAPK14 Q16539 1/20 0.32
PLA2G10 O15496 1/20 0.32
TSPO P30536 1/20 0.32
HDAC4 P56524 1/20 0.32
IL1R1 P14778 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27253389 0.98 KDM4E (0.38) L3MBTL1KDM4EATMKMT2APTGER4
SCHEMBL25852126 0.97 KDM4E (0.37) L3MBTL1KDM4EATMPTGER4EDNRB
SCHEMBL20633477 0.95 ATM (0.38) L3MBTL1KDM4EATMKMT2APTGER4
SCHEMBL27362232 0.93 EDNRB (0.33) L3MBTL1KDM4EATMPTGER4ALDH1A1
SCHEMBL25789741 0.93 KDM4E (0.41) L3MBTL1KDM4EATMKMT2AMEN1
SCHEMBL16545686 0.93 KDM4E (0.45) L3MBTL1KDM4EATMKMT2APTGER4
SCHEMBL25941324 0.92 KDM4E (0.38) L3MBTL1KDM4EATMKMT2APTGER4
SCHEMBL25671898 0.92 KDM4E (0.38) L3MBTL1KDM4EATMKMT2APTGER4
SCHEMBL27333585 0.92 KDM4E (0.39) L3MBTL1KDM4EATMKMT2APTGER4
SCHEMBL27333546 0.92 L3MBTL1 (0.42) L3MBTL1KDM4EATMKMT2APTGER4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024128698-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DIODE, ORGANIC OPTOELECTRONIC DIODE, AND DISPLAY DEVICE 삼성에스디아이 주식회사 2024-06-20 WO disclosed
WO-2024128699-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE 삼성에스디아이 주식회사 2024-06-20 WO disclosed
WO-2024128697-A1 COMPOSITION FOR OPTOELECTRONIC DEVICE AND ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE 삼성에스디아이 주식회사 2024-06-20 WO disclosed
EP-4219484-A1 ORGANIC LIGHT-EMITTING DEVICE, COMPOSITION FOR ORGANIC LAYER OF ORGANIC LIGHT-EMITTING DEVICE, AND METHOD FOR MANUFACTURING ORGANIC LIGHT-EMITTING DEVICE LT Materials Co., Ltd. (KR) 2023-08-02 EP disclosed
US-20230232717-A1 ORGANIC LIGHT-EMITTING DEVICE, COMPOSITION FOR ORGANIC LAYER OF ORGANIC LIGHTEMITTING DEVICE, AND METHOD FOR MANUFACTURING ORGANIC LIGHT-EMITTING DEVICE LT MATERIALS CO., LTD. (KR) 2023-07-20 US disclosed
US-20230232717-A1 ORGANIC LIGHT-EMITTING DEVICE, COMPOSITION FOR ORGANIC LAYER OF ORGANIC LIGHTEMITTING DEVICE, AND METHOD FOR MANUFACTURING ORGANIC LIGHT-EMITTING DEVICE LT MATERIALS CO., LTD. (KR) 2023-07-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230232717-A1 ORGANIC LIGHT-EMITTING DEVICE, COMPOSITION FOR ORGANIC LAYER OF ORGANIC LIGHTEMITTING DEVICE, AND METHOD FOR MANUFACTURING ORGANIC LIGHT-EMITTING DEVICE CYBA, AOX1, CYP1A1 L3MBTL1 571/4885KDM4E 2815/4885ATM 3929/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.