Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.39 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.39 |
| ▸ | GBA1 | P04062 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25833396 | 0.81 | AOC3 (0.43) | AOC3SLC6A2SLC6A4PYCR1GBA1 | |
| SCHEMBL25262039 | 0.81 | AOC3 (0.43) | AOC3SLC6A2SLC6A4PYCR1GBA1 | |
| SCHEMBL25857406 | 0.81 | AOC3 (0.43) | AOC3SLC6A2SLC6A4PYCR1GBA1 | |
| SCHEMBL31068674 | 0.80 | SLC6A2 (0.44) | AOC3SLC6A2SLC6A4PYCR1TSHR | |
| SCHEMBL25299430 | 0.80 | SLC6A2 (0.44) | AOC3SLC6A2SLC6A4PYCR1TSHR | |
| SCHEMBL25303719 | 0.70 | MAPK1 (0.37) | AOC3SLC6A2SLC6A4PYCR1GBA1 | |
| SCHEMBL25852812 | 0.69 | TAAR1 (0.63) | AOC3PYCR1TAAR1KMT2AATM | |
| SCHEMBL13122752 | 0.67 | ACP3 (0.40) | CTSBTSHRALDH1A1MAPTHPGD | |
| SCHEMBL14228172 | 0.66 | MEN1 (0.44) | ALDH1A1HPGDKMT2AATM | |
| SCHEMBL14228385 | 0.66 | WDR5 (0.46) | ALDH1A1HPGDRECQLKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023135233-A1 | AZAINDOLE DERIVATIVES AND THEIR USE AS ERK KINASE INHIBITORS | AGV DISCOVERY (FR) | 2023-07-20 | — | — | WO | disclosed |