Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 2/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.42 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.39 |
| ▸ | GBA1 | P04062 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | PNMT | P11086 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CCR5 | P51681 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25833396 | 1.00 | AOC3 (0.43) | AOC3SLC6A2SLC6A4PYCR1GBA1 | |
| SCHEMBL25262039 | 0.85 | AOC3 (0.43) | AOC3SLC6A2SLC6A4PYCR1GBA1 | |
| SCHEMBL31068674 | 0.84 | SLC6A2 (0.44) | AOC3SLC6A2SLC6A4PYCR1TSHR | |
| SCHEMBL25299430 | 0.84 | SLC6A2 (0.44) | AOC3SLC6A2SLC6A4PYCR1TSHR | |
| SCHEMBL25857409 | 0.84 | AOC3 (0.42) | AOC3SLC6A2SLC6A4MAOBALDH1A1 | |
| SCHEMBL25833514 | 0.81 | AOC3 (0.48) | AOC3SLC6A2SLC6A4PYCR1GBA1 | |
| SCHEMBL25852805 | 0.81 | AOC3 (0.40) | AOC3SLC6A2SLC6A4PYCR1GBA1 | |
| SCHEMBL25833347 | 0.80 | AOC3 (0.47) | AOC3SLC6A2SLC6A4PYCR1GBA1 | |
| SCHEMBL25832945 | 0.79 | SLC6A2 (0.52) | AOC3SLC6A2SLC6A4GBA1TSHR | |
| SCHEMBL25857362 | 0.79 | AOC3 (0.46) | AOC3SLC6A2SLC6A4PYCR1GBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4212531-A1 | AZAINDOLE DERIVATIVES AND THEIR USE AS ERK KINASE INHIBITORS | AGV Discovery (FR) | 2023-07-19 | — | — | EP | disclosed |