Fluorescein

Fluorescein

SCHEMBL2585358

O=C1OC(c2cc(Br)c(O)c(Br)c2)(c2cc(Br)c(O)c(Br)c2)c2ccccc21.O=C1OC2(c3ccc(O)cc3Oc3cc(O)ccc32)c2ccccc21

nearest known ligand 0.77

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FTO Q9C0B1 8/20 0.77
MAPT P10636 4/20 0.77
MEN1 O00255 3/20 0.77
KMT2A Q03164 3/20 0.77
PRMT1 Q99873 2/20 0.77
TDP1 Q9NUW8 2/20 0.77
HTT P42858 2/20 0.77
HPGD P15428 2/20 0.77
CYP2C19 P33261 1/20 0.77
RECQL P46063 1/20 0.77
BLM P54132 1/20 0.77
SMAD3 P84022 1/20 0.77
ACE2 Q9BYF1 1/20 0.77
AKR1C1 Q04828 1/20 0.74
HSP90AA1 P07900 2/20 0.70
TYMS P04818 2/20 0.57
DHFR P00374 2/20 0.57
LMNA P02545 3/20 0.55
GPR55 Q9Y2T6 2/20 0.55
ALOX12 P18054 2/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluorescein SCHEMBL30272223 0.88 FTO (1.00) FTOMAPTMEN1KMT2APRMT1
Fluorescein SCHEMBL29371199 0.88 FTO (1.00) FTOMAPTMEN1KMT2APRMT1
Fluorescein SCHEMBL3645090 0.88 FTO (1.00) FTOMAPTMEN1KMT2APRMT1
Fluorescein SCHEMBL16533 0.88 FTO (1.00) FTOMAPTMEN1KMT2APRMT1
Fluorescein SCHEMBL29388667 0.88 FTO (1.00) FTOMAPTMEN1KMT2APRMT1
Fluorescein SCHEMBL3459138 0.86 FTO (0.97) FTOMAPTMEN1KMT2APRMT1
Fluorescein SCHEMBL20503455 0.86 FTO (0.97) FTOMAPTMEN1KMT2APRMT1
Fluorescein SCHEMBL274138 0.86 FTO (0.97) FTOMAPTMEN1KMT2APRMT1
Fluorescein SCHEMBL21194999 0.86 FTO (0.97) FTOMAPTMEN1KMT2APRMT1
Fluorescein SCHEMBL21358817 0.86 FTO (0.97) FTOMAPTMEN1KMT2APRMT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8047839-B2 Methods of identifying orthodontic adhesives 3M INNOVATIVE PROPERTIES COMPANY (US) 2011-11-01 US disclosed
EP-1962770-A1 METHODS OF IDENTIFYING ORTHODONTIC ADHESIVES 3M Innovative Properties Company (US) 2008-09-03 EP disclosed
WO-2007075627-A1 METHODS OF IDENTIFYING ORTHODONTIC ADHESIVES 3M INNOVATIVE PROPERTIES COMPANY (US) 2007-07-05 WO disclosed
US-20070148609-A1 Methods of identifying orthodontic adhesives 3M INNOVATIVE PROPERTIES COMPANY 2007-06-28 US disclosed