SCHEMBL25853808

SCHEMBL25853808

CC(C)OC(=O)C1CCCCC1N(C)C

nearest known ligand 0.33

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 2/20 0.33
PDE4B Q07343 1/20 0.33
PKM P14618 1/20 0.32
POLB P06746 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
ALOX5 P09917 1/20 0.32
TSHR P16473 1/20 0.31
CTSK P43235 3/20 0.31
CTSL P07711 2/20 0.31
CTSB P07858 2/20 0.31
CTSH P09668 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1245703 0.82 TSHR (0.40) EPHX1PDE4BPOLBNPSR1TSHR
SCHEMBL1169668 0.82 TSHR (0.40) EPHX1PDE4BPOLBNPSR1TSHR
SCHEMBL1246352 0.82 TSHR (0.40) EPHX1PDE4BPOLBNPSR1TSHR
SCHEMBL1245700 0.82 TSHR (0.40) EPHX1PDE4BPOLBNPSR1TSHR
SCHEMBL1170184 0.81 TSHR (0.39) EPHX1PDE4BPOLBNPSR1TSHR
SCHEMBL19085525 0.79 SLC6A2 (0.40) EPHX1
SCHEMBL1169927 0.78 TSHR (0.40) EPHX1PDE4BPOLBNPSR1TSHR
SCHEMBL30553085 0.76 ACE (0.41)
SCHEMBL3288846 0.76 EPHX1 (0.50) EPHX1PDE4BPOLBNPSR1TSHR
SCHEMBL1296538 0.76 SLC6A2 (0.40) PDE4BPOLBNPSR1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230226096-A1 CIRCULAR RNA COMPOSITIONS AND METHODS ORNA THERAPEUTICS, INC. 2023-07-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230226096-A1 CIRCULAR RNA COMPOSITIONS AND METHODS RTCB, HNRNPA1, HNRNPAB EPHX1 4437/4885PDE4B 4322/4885PKM 1887/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.