SCHEMBL19085525

SCHEMBL19085525

COC(=O)C1CCCCC1N(C)C

nearest known ligand 0.40

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 2/20 0.40
SLC6A4 P31645 1/20 0.40
CHRM2 P08172 1/20 0.40
CHRM4 P08173 1/20 0.40
CHRM3 P20309 1/20 0.40
TAS1R3 Q7RTX0 1/20 0.37
TAS1R1 Q7RTX1 1/20 0.37
EPHX1 P07099 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4093715 0.83 TAS1R3 (0.35) SLC6A2SLC6A4CHRM2CHRM4CHRM3
SCHEMBL11514730 0.80 CHRM2 (0.48) SLC6A2SLC6A4CHRM2CHRM4CHRM3
SCHEMBL272354 0.80 CHRM2 (0.48) SLC6A2SLC6A4CHRM2CHRM4CHRM3
SCHEMBL13595131 0.80 CHRM2 (0.48) SLC6A2SLC6A4CHRM2CHRM4CHRM3
SCHEMBL8058857 0.80 CHRM2 (0.48) SLC6A2SLC6A4CHRM2CHRM4CHRM3
SCHEMBL25067241 0.79 EPHX1 (0.37) SLC6A2CHRM2CHRM3EPHX1
SCHEMBL25853808 0.79 EPHX1 (0.33) EPHX1
SCHEMBL28527891 0.78 SLC6A2 (0.50) SLC6A2SLC6A4CHRM2CHRM4CHRM3
SCHEMBL28866489 0.78 CHRM2 (0.47) SLC6A2SLC6A4CHRM2CHRM4CHRM3
SCHEMBL2606448 0.78 TSHR (0.39) SLC6A2SLC6A4CHRM2CHRM4CHRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023250375-A1 CIRCULAR RNA ENCODING CHIMERIC ANTIGEN RECEPTORS TARGETING BCMA ORNA THERAPEUTICS, INC. (US) 2023-12-28 WO disclosed
EP-4289951-A2 CIRCULAR RNA COMPOSITIONS AND METHODS Orna Therapeutics, Inc. (US) 2023-12-13 EP disclosed
WO-2023056033-A1 LIPID NANOPARTICLE COMPOSITIONS FOR DELIVERING CIRCULAR POLYNUCLEOTIDES ORNA THERAPEUTICS, INC. (US) 2023-04-06 WO disclosed
WO-2021226597-A2 CIRCULAR RNA COMPOSITIONS AND METHODS ORNA THERAPEUTICS, INC. (US) 2021-11-11 WO disclosed
WO-2021189059-A2 CIRCULAR RNA COMPOSITIONS AND METHODS ORNA THERAPEUTICS, INC. (US) 2021-09-23 WO disclosed
WO-2021113777-A2 CIRCULAR RNA COMPOSITIONS AND METHODS ORNA THERAPEUTICS, INC. (US) 2021-06-10 WO disclosed
WO-2021030701-A1 IMPROVED LIPID NANOPARTICLES FOR DELIVERY OF NUCLEIC ACIDS Acuitas Therapeutics, Inc. (CA) 2021-02-18 WO disclosed
WO-2018081480-A1 LIPID NANOPARTICLE FORMULATIONS Acuitas Therapeutics, Inc. (CA) 2018-05-03 WO disclosed
WO-2017117528-A1 LIPIDS AND LIPID NANOPARTICLE FORMULATIONS FOR DELIVERY OF NUCLEIC ACIDS Acuitas Therapeutics, Inc. (CA) 2017-07-06 WO disclosed