SCHEMBL2585424

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12180694	0.93	EZH2 (0.79)	EZH1EZH2EEDSUZ12PRMT3
	SCHEMBL12180731	0.92	EZH2 (0.88)	EZH1EZH2EEDSUZ12RBBP4
	Hydrochloric Acid SCHEMBL2590277	0.91	EZH2 (0.87)	EZH1EZH2EEDSUZ12RBBP4
	SCHEMBL30459645	0.89	EZH1 (1.00)	EZH1EZH2EEDSUZ12PRMT3
	SCHEMBL2591377	0.89	EZH1 (1.00)	EZH1EZH2EEDSUZ12PRMT3
	SCHEMBL12180173	0.88	EZH2 (0.86)	EZH1EZH2EEDSUZ12PRMT3
	SCHEMBL16786353	0.87	EZH2 (1.00)	EZH1EZH2EEDSUZ12RBBP4
	SCHEMBL2594803	0.86	EZH1 (0.82)	EZH1EZH2EEDSUZ12PRMT3
	SCHEMBL12180744	0.85	EZH2 (0.60)	EZH1EZH2EEDSUZ12PRMT3
	SCHEMBL2590359	0.85	EZH2 (0.78)	EZH1EZH2EEDSUZ12PRMT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.