Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.44 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.44 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16132816 | 0.89 | ALDH1A1 (0.54) | EHMT2EHMT1APOBEC3GSMN1; SMN2HPGD | |
| SCHEMBL1395632 | 0.89 | ALDH1A1 (0.54) | EHMT2EHMT1APOBEC3GSMN1; SMN2HPGD | |
| SCHEMBL24393470 | 0.85 | HDAC6 (0.46) | EHMT2EHMT1APOBEC3GSMN1; SMN2HPGD | |
| SCHEMBL25853943 | 0.85 | SMN1; SMN2 (0.44) | EHMT2EHMT1APOBEC3GSMN1; SMN2HPGD | |
| SCHEMBL836437 | 0.85 | SMN1; SMN2 (0.44) | EHMT2EHMT1APOBEC3GSMN1; SMN2HPGD | |
| SCHEMBL2157165 | 0.84 | SMN1; SMN2 (0.44) | EHMT2EHMT1APOBEC3GSMN1; SMN2HPGD | |
| SCHEMBL19193751 | 0.83 | EHMT2 (0.44) | EHMT2EHMT1APOBEC3GSMN1; SMN2HPGD | |
| SCHEMBL18958956 | 0.82 | LMNA (0.40) | EHMT2EHMT1APOBEC3GSMN1; SMN2HPGD | |
| SCHEMBL2610936 | 0.80 | EHMT2 (0.52) | EHMT2EHMT1APOBEC3GSMN1; SMN2HPGD | |
| SCHEMBL31005434 | 0.80 | LMNA (0.39) | EHMT2EHMT1APOBEC3GSMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11696956-B2 | Bicyclic peptide ligands specific for EphA2 | BICYCLETX LIMITED (GB) | 2023-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11696956-B2 | Bicyclic peptide ligands specific for EphA2 | EPHA2, EPHB2, ERBB2 | EHMT2 1108/4885EHMT1 2040/4885APOBEC3G 2333/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.