Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | RECQL | P46063 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.51 |
| ▸ | HTR2C | P28335 | 4/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | CHRNA7 | P36544 | 7/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19633219 | 0.81 | AGPAT2 (0.40) | HTR2BMEN1KMT2ATP53CYP1A2 | |
| SCHEMBL19633019 | 0.80 | GRM4 (0.37) | HTR2BMEN1KMT2ATP53CYP1A2 | |
| Hydrochloric Acid SCHEMBL30464353 | 0.80 | GRM4 (0.37) | HTR2BMEN1KMT2ATP53CYP1A2 | |
| SCHEMBL25597800 | 0.79 | HTR2B (0.54) | HTR2BMEN1KMT2ATP53CYP1A2 | |
| SCHEMBL19614843 | 0.78 | GRM4 (0.36) | HTR2BMEN1KMT2ATP53CYP1A2 | |
| SCHEMBL13594562 | 0.78 | MAOB (0.59) | MAOBLMNA | |
| SCHEMBL19636843 | 0.78 | GRM4 (0.35) | HTR2BMEN1KMT2ATP53CYP1A2 | |
| Hydrochloric Acid SCHEMBL19614868 | 0.76 | ERBB2 (0.38) | MAPTKDM4EHTR2CHIF1AAGPAT2 | |
| SCHEMBL21379454 | 0.75 | HTR2C (0.60) | HTR2BMEN1KMT2ATP53CYP1A2 | |
| SCHEMBL19538866 | 0.75 | MAPT (0.59) | HTR2BMEN1KMT2ATP53CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3458069-B1 | PYRROLOBENZODIAZEPINES AND CONJUGATES THEREOF | MERSANA THERAPEUTICS INC (US) | 2023-07-05 | — | — | EP | disclosed |