Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22694557 | 0.84 | RXFP1 (0.44) | RXFP1TDP1ALDH1A1L3MBTL1CYP3A4 | |
| SCHEMBL13282267 | 0.82 | ALDH1A1 (0.53) | RXFP1TDP1ALDH1A1L3MBTL1CYP3A4 | |
| SCHEMBL24920157 | 0.81 | RXFP1 (0.51) | RXFP1TDP1ALDH1A1L3MBTL1CYP3A4 | |
| SCHEMBL21706332 | 0.81 | RXFP1 (0.41) | RXFP1TDP1ALDH1A1L3MBTL1CYP3A4 | |
| SCHEMBL21566741 | 0.81 | RXFP1 (0.41) | RXFP1TDP1ALDH1A1L3MBTL1CYP3A4 | |
| SCHEMBL21569847 | 0.79 | POLB (0.38) | ALDH1A1CYP3A4THRBALOX15TSHR | |
| SCHEMBL9911536 | 0.79 | NPSR1 (0.58) | ALDH1A1NPSR1FFAR1 | |
| SCHEMBL13254061 | 0.77 | RXFP1 (0.44) | RXFP1TDP1ALDH1A1L3MBTL1CYP3A4 | |
| SCHEMBL12871153 | 0.77 | TDP1 (0.46) | RXFP1TDP1ALDH1A1L3MBTL1CYP3A4 | |
| SCHEMBL28688598 | 0.76 | SMN1; SMN2 (0.44) | RXFP1ALDH1A1HSD17B10LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230381321-A1 | CAMPTOTHECIN CONJUGATES | SEAGEN INC. | 2023-11-30 | — | — | US | disclosed |
| WO-2023201234-A2 | ANTI-VARIABLE MUC1* ANTIBODIES AND USES THEREOF | MINERVA BIOTECHNOLOGIES CORPORATION (US) | 2023-10-19 | — | — | WO | disclosed |
| WO-2023135397-A1 | PROCESS FOR THE PREPARATION OF ANTIBODY-DRUG CONJUGATES | MC SAF (FR) | 2023-07-20 | — | — | WO | disclosed |
| WO-2023131219-A1 | CONJUGATES, COMPOSITIONS AND METHODS OF USE | VIRTUOSO BINCO, INC. (US) | 2023-07-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230381321-A1 | CAMPTOTHECIN CONJUGATES | DCLRE1A, TOP2A, PAICS | RXFP1 4627/4885TDP1 741/4885ALDH1A1 1069/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.