SCHEMBL25855192

SCHEMBL25855192

O=C(O)c1ccc2c(c1)ncc1ccncc12

nearest known ligand 0.59

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CSNK2A2 P19784 19/20 0.59
CSNK2B P67870 19/20 0.59
CSNK2A1 P68400 7/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29900275 1.00 CSNK2A2 (0.59) CSNK2A2CSNK2BCSNK2A1
SCHEMBL29900222 0.87 CSNK2A2 (0.55) CSNK2A2CSNK2BCSNK2A1
SCHEMBL30694774 0.83 CSNK2A1 (0.58) CSNK2A2CSNK2BCSNK2A1
SCHEMBL28327537 0.81 KDM4E (0.55) CSNK2A2CSNK2BCSNK2A1
SCHEMBL20718474 0.80 HIPK2 (0.72) CSNK2A2CSNK2BCSNK2A1
SCHEMBL30464338 0.80 HIPK2 (0.72) CSNK2A2CSNK2BCSNK2A1
SCHEMBL15486463 0.78 CSNK2A2 (0.69) CSNK2A2CSNK2BCSNK2A1
SCHEMBL11932365 0.77 CSNK2A2 (0.67) CSNK2A2CSNK2BCSNK2A1
SCHEMBL11411063 0.76 MAPK10 (0.58) CSNK2A2CSNK2BCSNK2A1
SCHEMBL31712837 0.75 MAPK10 (0.48) CSNK2A2CSNK2BCSNK2A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023107723-A2 METHODS FOR TREATING NEUROLOGICAL DISORDERS PROTHENA BIOSCIENCES LIMITED (IE) 2023-06-15 WO disclosed