Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK10 | P53779 | 8/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CSNK2A2 | P19784 | 4/20 | 0.46 |
| ▸ | CSNK2B | P67870 | 4/20 | 0.46 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.44 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.44 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 2/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.41 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.41 |
| ▸ | CHEK2 | O96017 | 3/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.40 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | PAK4 | O96013 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30504719 | 0.88 | CSNK2A2 (0.46) | MAPK10KDM4EHTTCSNK2A2CSNK2B | |
| SCHEMBL29900222 | 0.88 | CSNK2A2 (0.55) | KDM4EHTTCSNK2A2CSNK2BPKN1 | |
| SCHEMBL31712862 | 0.79 | KDM4E (0.48) | MAPK10KDM4EHTTCSNK2A2CSNK2B | |
| SCHEMBL11411063 | 0.78 | MAPK10 (0.58) | MAPK10CSNK2A2CSNK2BHIPK2PIM1 | |
| SCHEMBL31712895 | 0.78 | CSNK2A2 (0.43) | CSNK2A2CSNK2BPKN1PKN2AR | |
| SCHEMBL5636056 | 0.75 | AR (0.45) | KDM4EHTTHIPK2ARPIM1 | |
| SCHEMBL5801279 | 0.75 | AR (0.48) | KDM4EHTTCSNK2A2CSNK2BPKN1 | |
| SCHEMBL29900275 | 0.75 | CSNK2A2 (0.59) | CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL25855192 | 0.75 | CSNK2A2 (0.59) | CSNK2A2CSNK2BCSNK2A1 | |
| Hydrochloric Acid SCHEMBL2366806 | 0.74 | AR (0.44) | KDM4EHTTHIPK2ARPIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4251624-B1 | TRICYCLIC CARBOXAMIDE DERIVATIVES AS PRMT5 INHIBITORS | AMGEN INC (US) | 2025-10-29 | — | — | EP | claimed |