SCHEMBL25855247 — predicted protein targets

Predicted protein targets (top 11)

	gene	UniProt	supporting neighbours	confidence
▸	NLRP3	Q96P20	8/20	0.54

▸	IL1B	P01584	2/20	0.33

▸	GBA1	P04062	1/20	0.32

▸	JAK2	O60674	1/20	0.32

▸	JAK1	P23458	1/20	0.32

▸	KCNH2	Q12809	1/20	0.32

▸	CD38	P28907	1/20	0.32

▸	PIM1	P11309	1/20	0.30

▸	PIM2	Q9P1W9	1/20	0.30

▸	BTK	Q06187	1/20	0.30

▸	GPR84	Q9NQS5	1/20	0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL25855246	0.95	NLRP3 (0.55)	NLRP3IL1BGPR84
SCHEMBL30488599	0.84	KDM4E (0.41)	NLRP3IL1BGBA1JAK2JAK1
SCHEMBL25302310	0.84	KDM4E (0.41)	NLRP3IL1BGBA1JAK2JAK1
SCHEMBL25302312	0.84	KDM4E (0.41)	NLRP3IL1BGBA1JAK2JAK1
SCHEMBL25855457	0.83	NLRP3 (0.49)	NLRP3IL1B
SCHEMBL25855250	0.82	NLRP3 (0.54)	NLRP3IL1B
SCHEMBL25855444	0.82	NLRP3 (0.48)	NLRP3IL1B
SCHEMBL25302297	0.82	NLRP3 (0.57)	NLRP3IL1B
SCHEMBL25303433	0.82	NLRP3 (0.57)	NLRP3IL1B
SCHEMBL25854954	0.82	NLRP3 (0.57)	NLRP3IL1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2023131277-A1	NLRP3 INFLAMMASOME INHIBITOR AND USES THEREOF	药捷安康(南京)科技股份有限公司	2023-07-13	—	—	WO	disclosed