Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 8/20 | 0.55 |
| ▸ | IL1B | P01584 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.30 |
| ▸ | MAT2A | P31153 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25855247 | 0.95 | NLRP3 (0.54) | NLRP3IL1BGPR84 | |
| SCHEMBL25855444 | 0.83 | NLRP3 (0.48) | NLRP3IL1B | |
| SCHEMBL25305252 | 0.83 | KDM4E (0.38) | NLRP3MAT2A | |
| SCHEMBL30488554 | 0.83 | KDM4E (0.38) | NLRP3MAT2A | |
| SCHEMBL25256486 | 0.83 | KDM4E (0.38) | NLRP3MAT2A | |
| SCHEMBL25302297 | 0.82 | NLRP3 (0.57) | NLRP3IL1B | |
| SCHEMBL25303433 | 0.82 | NLRP3 (0.57) | NLRP3IL1B | |
| SCHEMBL25854954 | 0.82 | NLRP3 (0.57) | NLRP3IL1B | |
| SCHEMBL30488623 | 0.82 | NLRP3 (0.55) | NLRP3IL1B | |
| SCHEMBL25294814 | 0.82 | NLRP3 (0.55) | NLRP3IL1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131277-A1 | NLRP3 INFLAMMASOME INHIBITOR AND USES THEREOF | 药捷安康(南京)科技股份有限公司 | 2023-07-13 | — | — | WO | disclosed |