Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.31 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.31 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2585537 | 1.00 | TP53 (0.32) | TP53MEN1KMT2AGRIK1GRIK2 | |
| SCHEMBL4905015 | 0.91 | — | — | |
| SCHEMBL18326997 | 0.91 | — | — | |
| SCHEMBL5177494 | 0.91 | — | — | |
| SCHEMBL9034035 | 0.80 | — | — | |
| SCHEMBL7164919 | 0.80 | GABRP (0.32) | — | |
| SCHEMBL3760042 | 0.80 | GABRP (0.32) | — | |
| SCHEMBL9034041 | 0.80 | — | — | |
| SCHEMBL9055419 | 0.77 | ACHE (0.33) | — | |
| SCHEMBL9055427 | 0.77 | ACHE (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117396473-A | Imidazopyridinyl inhibitors of plasma kallikrein | 武田药品工业株式会社 | 2024-01-12 | — | — | CN | disclosed |
| CN-115551864-A | Substituted tricyclic amides, analogs thereof, and methods of using the same | 爱彼特生物制药公司 | 2022-12-30 | — | — | CN | disclosed |
| EP-2566850-B1 | INDUSTRIAL PROCESS FOR THE SYNTHESIS OF IVABRADINE HYDROBROMIDE SALT | RICHTER GEDEON NYRT (HU) | 2018-04-11 | — | — | EP | disclosed |
| EP-2566850-A1 | INDUSTRIAL PROCESS FOR THE SYNTHESIS OF IVABRADINE SALTS | Richter Gedeon Nyrt. (HU) | 2013-03-13 | — | — | EP | disclosed |
| WO-2011138625-A1 | INDUSTRIAL PROCESS FOR THE SYNTHESIS OF IVABRADINE SALTS | RICHTER GEDEON NYRT. (HU) | 2011-11-10 | — | — | WO | disclosed |