Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.63 |
| ▸ | MAPT | P10636 | 14/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11448463 | 0.98 | MAPT (0.64) | HPGDMAPTALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL12478410 | 0.87 | MAPT (0.73) | HPGDMAPTALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL21066338 | 0.87 | MAPT (0.73) | HPGDMAPTALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL19899574 | 0.85 | MAPT (0.75) | HPGDMAPTALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL25855470 | 0.85 | HPGD (0.73) | HPGDMAPTALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL7374614 | 0.84 | MAPT (0.65) | HPGDMAPTALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL12856216 | 0.84 | MAPT (0.78) | HPGDMAPTALDH1A1L3MBTL1LMNA | |
| SCHEMBL12497122 | 0.84 | MAPT (0.54) | HPGDMAPTALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL29039490 | 0.81 | HPGD (0.63) | HPGDMAPTALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL25337059 | 0.80 | MAPT (0.61) | HPGDMAPTALDH1A1CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230212158-A1 | SMALL MOLECULE INHIBITORS OF GALECTIN-3 | BRISTOL MYERS SQUIBB CO (US) | 2023-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230212158-A1 | SMALL MOLECULE INHIBITORS OF GALECTIN-3 | LGALS3, LGALS1, LGALS3BP | HPGD 3117/4885MAPT 3151/4885ALDH1A1 2713/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.