SCHEMBL25855616

SCHEMBL25855616

C=C(C)C(=O)OCCCc1ccc(-c2ccc3c(sc4c(OC)c(OC(=O)C(=C)C)ccc43)c2C)cc1

nearest known ligand 0.31

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TNKS2 Q9H2K2 1/20 0.31
POLB P06746 1/20 0.31
APEX1 P27695 1/20 0.31
HTT P42858 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
TSHR P16473 2/20 0.30
RARB P10826 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25855748 0.93 TNKS2 (0.33) TNKS2POLBAPEX1HTTTDP1
SCHEMBL25855308 0.93 TNKS2 (0.31) TNKS2POLBAPEX1HTTTDP1
SCHEMBL25855187 0.92 POLB (0.33) POLBAPEX1HTTTDP1TSHR
SCHEMBL25855605 0.91 MPL (0.32) TNKS2POLBAPEX1HTTTDP1
SCHEMBL25856228 0.89 FFAR4 (0.30)
SCHEMBL25854858 0.89 MPL (0.32) POLBAPEX1HTTTDP1TSHR
SCHEMBL25855860 0.88 FFAR4 (0.33)
SCHEMBL25855755 0.88 NR1H2 (0.31)
SCHEMBL25856006 0.86 NR1H2 (0.33) POLBAPEX1HTTTDP1
SCHEMBL25854938 0.86 MET (0.31) TNKS2POLBAPEX1HTTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023134598-A1 POLYMERISABLE COMPOUND, COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE 烟台显华科技集团股份有限公司 2023-07-20 WO disclosed
WO-2023134596-A1 NEGATIVE DIELECTRIC ANISOTROPIC LIQUID CRYSTAL COMPOSITION, OPTICAL ANISOTROPIER, AND LIQUID CRYSTAL DISPLAY COMPONENT 烟台显华科技集团股份有限公司 2023-07-20 WO disclosed