SCHEMBL25855605

SCHEMBL25855605

C=C(C)C(=O)OCCCc1ccc(-c2ccc3c(sc4c(OC)c(OC(=O)C(=C)C)ccc43)c2F)cc1

nearest known ligand 0.32

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MPL P40238 6/20 0.32
TNKS2 Q9H2K2 1/20 0.31
POLB P06746 1/20 0.31
APEX1 P27695 1/20 0.31
HTT P42858 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
FFAR4 Q5NUL3 1/20 0.30
TSHR P16473 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25854938 0.94 MET (0.31) TNKS2POLBAPEX1HTTTDP1
SCHEMBL25855748 0.93 TNKS2 (0.33) TNKS2POLBAPEX1HTTTDP1
SCHEMBL25869453 0.92 POLB (0.33) MPLPOLBAPEX1HTTTDP1
SCHEMBL25855616 0.91 TNKS2 (0.31) TNKS2POLBAPEX1HTTTDP1
SCHEMBL25856224 0.90 MPL (0.31) MPLPOLBAPEX1HTTTDP1
SCHEMBL25855183 0.90 MPL (0.34) MPLPOLBAPEX1HTTTDP1
SCHEMBL25855755 0.89 NR1H2 (0.31)
SCHEMBL25855860 0.89 FFAR4 (0.33) FFAR4
SCHEMBL25855999 0.87 NR1H2 (0.33) POLBAPEX1HTTTDP1
SCHEMBL25853776 0.86 POLB (0.34) POLBAPEX1HTTTDP1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023134598-A1 POLYMERISABLE COMPOUND, COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE 烟台显华科技集团股份有限公司 2023-07-20 WO disclosed
WO-2023134596-A1 NEGATIVE DIELECTRIC ANISOTROPIC LIQUID CRYSTAL COMPOSITION, OPTICAL ANISOTROPIER, AND LIQUID CRYSTAL DISPLAY COMPONENT 烟台显华科技集团股份有限公司 2023-07-20 WO disclosed