SCHEMBL25855668 — predicted protein targets

Predicted protein targets (top 13)

	gene	UniProt	supporting neighbours	confidence
▸	NLRP3	Q96P20	4/20	0.47

▸	IL1B	P01584	9/20	0.44

▸	TNF	P01375	2/20	0.42

▸	KDM4E	B2RXH2	2/20	0.36

▸	HSD17B10	Q99714	1/20	0.36

▸	GAA	P10253	2/20	0.34

▸	ALDH1A1	P00352	2/20	0.34

▸	LMNA	P02545	1/20	0.34

▸	HTT	P42858	1/20	0.34

▸	KMT2A	Q03164	1/20	0.34

▸	IRAK4	Q9NWZ3	1/20	0.34

▸	MAPT	P10636	1/20	0.31

▸	KRAS	P01116	2/20	0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL25864315	0.89	NLRP3 (0.39)	NLRP3IL1BTNFKDM4EHSD17B10
SCHEMBL25854743	0.89	NLRP3 (0.46)	NLRP3IL1BTNFIRAK4
SCHEMBL25855821	0.89	NLRP3 (0.46)	NLRP3IL1BTNFKDM4EHSD17B10
SCHEMBL25855826	0.89	NLRP3 (0.46)	NLRP3IL1BTNFKDM4EHSD17B10
SCHEMBL25854626	0.88	NLRP3 (0.44)	NLRP3IL1BTNFIRAK4
SCHEMBL25854741	0.88	NLRP3 (0.46)	NLRP3IL1BTNFIRAK4
SCHEMBL25855820	0.88	NLRP3 (0.48)	NLRP3IL1BTNFKDM4EHSD17B10
SCHEMBL25855827	0.88	NLRP3 (0.48)	NLRP3IL1BTNFKDM4EHSD17B10
SCHEMBL25854629	0.87	NLRP3 (0.44)	NLRP3IL1BTNFKDM4EIRAK4
SCHEMBL25855825	0.87	NLRP3 (0.50)	NLRP3IL1BTNFKDM4EHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2023131277-A1	NLRP3 INFLAMMASOME INHIBITOR AND USES THEREOF	药捷安康(南京)科技股份有限公司	2023-07-13	—	—	WO	disclosed