SCHEMBL25855825 — predicted protein targets

Predicted protein targets (top 15)

	gene	UniProt	supporting neighbours	confidence
▸	NLRP3	Q96P20	6/20	0.50

▸	IL1B	P01584	9/20	0.46

▸	TNF	P01375	2/20	0.46

▸	KDM4E	B2RXH2	2/20	0.33

▸	HSD17B10	Q99714	1/20	0.33

▸	KCNH2	Q12809	1/20	0.32

▸	KMT2A	Q03164	2/20	0.32

▸	ALDH1A1	P00352	1/20	0.32

▸	LMNA	P02545	1/20	0.32

▸	GAA	P10253	1/20	0.32

▸	HTT	P42858	1/20	0.32

▸	CHEK1	O14757	2/20	0.31

▸	CHEK2	O96017	2/20	0.31

▸	MEN1	O00255	1/20	0.30

▸	HSP90AA1	P07900	1/20	0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL25864407	0.90	NLRP3 (0.42)	NLRP3IL1BTNFKDM4EHSD17B10
SCHEMBL25855827	0.89	NLRP3 (0.48)	NLRP3IL1BTNFKDM4EHSD17B10
SCHEMBL25855821	0.88	NLRP3 (0.46)	NLRP3IL1BTNFKDM4EHSD17B10
SCHEMBL25855668	0.87	NLRP3 (0.47)	NLRP3IL1BTNFKDM4EHSD17B10
SCHEMBL25855823	0.86	NLRP3 (0.44)	NLRP3IL1BTNFKDM4EHSD17B10
SCHEMBL25855820	0.85	NLRP3 (0.48)	NLRP3IL1BTNFKDM4EHSD17B10
SCHEMBL25855826	0.84	NLRP3 (0.46)	NLRP3IL1BTNFKDM4EHSD17B10
SCHEMBL25854844	0.84	NLRP3 (0.64)	NLRP3IL1BTNFKCNH2
SCHEMBL24574826	0.83	NLRP3 (0.70)	NLRP3IL1BTNFKCNH2CHEK1
SCHEMBL26132420	0.83	NLRP3 (0.70)	NLRP3IL1BTNFKCNH2CHEK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2023131277-A1	NLRP3 INFLAMMASOME INHIBITOR AND USES THEREOF	药捷安康(南京)科技股份有限公司	2023-07-13	—	—	WO	disclosed