Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 3/20 | 0.33 |
| ▸ | CTSK | P43235 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.31 |
| ▸ | CTSB | P07858 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | MMP8 | P22894 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17486950 | 0.76 | DGAT1 (0.43) | DGAT1CA1CA2CA7TSHR | |
| SCHEMBL11062288 | 0.76 | MAPK1 (0.36) | MAPK1TSHRCYP2D6 | |
| SCHEMBL11386892 | 0.76 | MAPK1 (0.36) | MAPK1TSHR | |
| SCHEMBL28758526 | 0.75 | CYP4F2 (0.39) | TSHRMMP8 | |
| SCHEMBL20725398 | 0.74 | MAPK1 (0.34) | MAPK1TSHR | |
| SCHEMBL26316213 | 0.72 | DGAT1 (0.40) | DGAT1GAA | |
| SCHEMBL28694851 | 0.71 | DGAT1 (0.39) | DGAT1CTSK | |
| SCHEMBL6366841 | 0.70 | TSHR (0.43) | DGAT1MAPK1CA1CA2CA7 | |
| SCHEMBL28077386 | 0.70 | DGAT1 (0.41) | DGAT1MAPK1CA1CA2CA7 | |
| SCHEMBL28851160 | 0.70 | DGAT1 (0.41) | DGAT1CA1CA2CA7CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3609889-B1 | SMALL MOLECULES | UNIV DUNDEE (GB) | 2023-07-05 | — | — | EP | disclosed |