SCHEMBL26316213

SCHEMBL26316213

CC(=O)COC(C)(C)C(=O)OC(C)(C)C

nearest known ligand 0.40

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 1/20 0.40
GAA P10253 1/20 0.31
APLNR P35414 1/20 0.30
HDAC1 Q13547 1/20 0.30
HDAC2 Q92769 1/20 0.30
HDAC6 Q9UBN7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24034051 0.83 DGAT1 (0.38) DGAT1
SCHEMBL2015627 0.80 MGAM (0.37) DGAT1GAA
SCHEMBL17486950 0.77 DGAT1 (0.43) DGAT1HDAC1HDAC2HDAC6
SCHEMBL26316122 0.77 CYP4F2 (0.50) GAA
SCHEMBL6686581 0.76
SCHEMBL31364246 0.73 HDAC6 (0.35) DGAT1GAAAPLNRHDAC1HDAC2
SCHEMBL28694851 0.72 DGAT1 (0.39) DGAT1
SCHEMBL25855692 0.72 DGAT1 (0.39) DGAT1GAA
SCHEMBL12332053 0.72 DGAT1 (0.46) DGAT1GAA
SCHEMBL10295968 0.71 DGAT1 (0.41) DGAT1GAAHDAC1HDAC2HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4149941-B1 CERTAIN CHEMICAL COMPOSITIONS AND METHODS OF USE THEREOF ALGEN BIOTECHNOLOGIES INC (US) 2025-09-03 EP disclosed
US-12264152-B2 Certain chemical compositions and methods of use thereof ALGEN BIOTECHNOLOGIES, INC. (US) 2025-04-01 US disclosed
US-20230295135-A1 CERTAIN CHEMICAL COMPOSITIONS AND METHODS OF USE THEREOF ALGEN BIOTECHNOLOGIES, INC. 2023-09-21 US disclosed
US-20230295135-A1 CERTAIN CHEMICAL COMPOSITIONS AND METHODS OF USE THEREOF ALGEN BIOTECHNOLOGIES, INC. 2023-09-21 US disclosed
CN-116261561-A Certain chemical compositions and methods of use thereof 奧基生物技术有限公司 2023-06-13 CN disclosed
EP-4149941-A1 CERTAIN CHEMICAL COMPOSITIONS AND METHODS OF USE THEREOF Algen Biotechnologies, Inc. (US) 2023-03-22 EP disclosed
US-11591322-B2 Certain chemical compositions and methods of use thereof ALGEN BIOTECHNOLOGIES, INC. (US) 2023-02-28 US disclosed
US-20220289725-A1 CERTAIN CHEMICAL COMPOSITIONS AND METHODS OF USE THEREOF ALGEN BIOTECHNOLOGIES, INC. 2022-09-15 US disclosed
WO-2021231892-A1 CERTAIN CHEMICAL COMPOSITIONS AND METHODS OF USE THEREOF ALGEN BIOTECHNOLOGIES, INC. (US) 2021-11-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220289725-A1 CERTAIN CHEMICAL COMPOSITIONS AND METHODS OF USE THEREOF CDK9, CDK19, CDK6 DGAT1 2229/4885GAA 967/4885APLNR 3607/4885
US-11591322-B2 Certain chemical compositions and methods of use thereof CDK9, CDK19, CDK6 DGAT1 2229/4885GAA 967/4885APLNR 3607/4885
US-20230295135-A1 CERTAIN CHEMICAL COMPOSITIONS AND METHODS OF USE THEREOF CDK9, CDK19, CDK6 DGAT1 2229/4885GAA 967/4885APLNR 3607/4885
US-12264152-B2 Certain chemical compositions and methods of use thereof CDK9, CDK19, CDK6 DGAT1 2229/4885GAA 967/4885APLNR 3607/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.