⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3915138 | 0.96 | — | — | |
| SCHEMBL2583607 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL2587299 | 0.76 | — | — | |
| SCHEMBL20203375 | 0.76 | — | — | |
| SCHEMBL29012275 | 0.74 | DNM1 (0.60) | — | |
| SCHEMBL27474409 | 0.74 | DNM1 (0.60) | — | |
| SCHEMBL29363073 | 0.74 | DNM1 (0.60) | — | |
| SCHEMBL5536819 | 0.74 | DNM1 (0.60) | — | |
| SCHEMBL27297974 | 0.74 | DNM1 (0.60) | — | |
| SCHEMBL11322312 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2566850-B1 | INDUSTRIAL PROCESS FOR THE SYNTHESIS OF IVABRADINE HYDROBROMIDE SALT | RICHTER GEDEON NYRT (HU) | 2018-04-11 | — | — | EP | disclosed |
| EP-2566850-A1 | INDUSTRIAL PROCESS FOR THE SYNTHESIS OF IVABRADINE SALTS | Richter Gedeon Nyrt. (HU) | 2013-03-13 | — | — | EP | disclosed |
| WO-2011138625-A1 | INDUSTRIAL PROCESS FOR THE SYNTHESIS OF IVABRADINE SALTS | RICHTER GEDEON NYRT. (HU) | 2011-11-10 | — | — | WO | disclosed |