Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 6/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 5/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26034651 | 0.93 | ALDH1A1 (0.47) | ALDH1A1NPC1TP53NR1H4HCAR2 | |
| SCHEMBL25837267 | 0.91 | CXCR4 (0.49) | ALDH1A1NPC1TP53NR1H4HCAR2 | |
| SCHEMBL25836975 | 0.90 | ALDH1A1 (0.48) | ALDH1A1NPC1TP53NR1H4SMPD1 | |
| SCHEMBL25837270 | 0.90 | MAPT (0.51) | ALDH1A1NPC1TP53NR1H4SMPD1 | |
| SCHEMBL25837025 | 0.85 | TP53 (0.51) | ALDH1A1NPC1TP53NR1H4SMPD1 | |
| SCHEMBL25851756 | 0.84 | TP53 (0.50) | ALDH1A1NPC1TP53NR1H4SMPD1 | |
| SCHEMBL25855965 | 0.83 | CXCR4 (0.47) | ALDH1A1NPC1TP53NR1H4SMPD1 | |
| SCHEMBL25836944 | 0.83 | TP53 (0.49) | ALDH1A1NPC1TP53NR1H4SMPD1 | |
| SCHEMBL25836967 | 0.82 | CXCR4 (0.49) | ALDH1A1NPC1TP53NR1H4SMPD1 | |
| SCHEMBL24340636 | 0.80 | NPC1 (0.62) | ALDH1A1NPC1TP53POLBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230226193-A1 | LIPID CONJUGATES FOR THE DELIVERY OF THERAPEUTIC AGENTS | Arrowhead Pharmaceuticals, Inc. | 2023-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230226193-A1 | LIPID CONJUGATES FOR THE DELIVERY OF THERAPEUTIC AGENTS | CPT1B, MUSK, MYLK2 | ALDH1A1 1330/4885NPC1 561/4885TP53 4012/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.