Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.66 |
| ▸ | IL1B | P01584 | 7/20 | 0.37 |
| ▸ | TNF | P01375 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25864431 | 0.90 | NLRP3 (0.54) | NLRP3KDM4EALDH1A1GAAHPGD | |
| SCHEMBL25862823 | 0.89 | NLRP3 (0.63) | NLRP3IL1BTNF | |
| SCHEMBL29030495 | 0.89 | NLRP3 (0.63) | NLRP3IL1BTNF | |
| SCHEMBL30488524 | 0.89 | NLRP3 (0.63) | NLRP3IL1BTNF | |
| SCHEMBL25855975 | 0.87 | NLRP3 (0.60) | NLRP3IL1BTNF | |
| SCHEMBL25855974 | 0.84 | NLRP3 (0.46) | NLRP3IL1BTNFKDM4EALDH1A1 | |
| SCHEMBL25856087 | 0.83 | NLRP3 (0.74) | NLRP3IL1BTNF | |
| SCHEMBL30488489 | 0.80 | NLRP3 (0.81) | NLRP3IL1BTNF | |
| SCHEMBL29030532 | 0.80 | NLRP3 (0.81) | NLRP3IL1BTNF | |
| SCHEMBL28934559 | 0.80 | NLRP3 (1.00) | NLRP3IL1BTNF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131277-A1 | NLRP3 INFLAMMASOME INHIBITOR AND USES THEREOF | 药捷安康(南京)科技股份有限公司 | 2023-07-13 | — | — | WO | disclosed |