Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25855976 | 0.90 | NLRP3 (0.66) | NLRP3KDM4EALDH1A1GAAHPGD | |
| SCHEMBL25863872 | 0.89 | NLRP3 (0.51) | NLRP3 | |
| SCHEMBL25864430 | 0.88 | NLRP3 (0.49) | NLRP3 | |
| SCHEMBL25864428 | 0.85 | NLRP3 (0.36) | NLRP3KDM4EALDH1A1GAA | |
| SCHEMBL25864508 | 0.83 | NLRP3 (0.58) | NLRP3 | |
| SCHEMBL25863877 | 0.81 | NLRP3 (0.50) | NLRP3 | |
| SCHEMBL25864640 | 0.80 | NLRP3 (0.65) | NLRP3 | |
| SCHEMBL29030495 | 0.79 | NLRP3 (0.63) | NLRP3 | |
| SCHEMBL30488524 | 0.79 | NLRP3 (0.63) | NLRP3 | |
| SCHEMBL25863753 | 0.79 | NLRP3 (0.63) | NLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131277-A1 | NLRP3 INFLAMMASOME INHIBITOR AND USES THEREOF | 药捷安康(南京)科技股份有限公司 | 2023-07-13 | — | — | WO | disclosed |