Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.72 |
| ▸ | NPC1 | O15118 | 8/20 | 0.72 |
| ▸ | RAB9A | P51151 | 8/20 | 0.72 |
| ▸ | TSHR | P16473 | 3/20 | 0.72 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.71 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.71 |
| ▸ | TP53 | P04637 | 7/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.69 |
| ▸ | POLB | P06746 | 3/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.62 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.59 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.59 |
| ▸ | RELA | Q04206 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | CASP3 | P42574 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.59 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9063892 | 0.85 | SMN1; SMN2 (0.66) | SMN1; SMN2NPC1RAB9ATSHRCYP1A2 | |
| SCHEMBL31165739 | 0.85 | CYP1A2 (0.69) | SMN1; SMN2NPC1RAB9ATSHRCYP1A2 | |
| SCHEMBL8348993 | 0.84 | CYP1A2 (0.73) | SMN1; SMN2NPC1RAB9ACYP1A2CYP2C19 | |
| SCHEMBL20221777 | 0.80 | HPGD (0.70) | SMN1; SMN2NPC1RAB9ATSHRTP53 | |
| SCHEMBL11887778 | 0.80 | NPSR1 (0.76) | SMN1; SMN2NPC1RAB9ATSHRTP53 | |
| SCHEMBL16157136 | 0.80 | MAPT (0.70) | SMN1; SMN2NPC1RAB9ATSHRTP53 | |
| SCHEMBL16157045 | 0.80 | POLB (1.00) | SMN1; SMN2NPC1RAB9ATSHRCYP1A2 | |
| SCHEMBL17068761 | 0.77 | SMN1; SMN2 (0.64) | SMN1; SMN2NPC1RAB9ATSHRTP53 | |
| SCHEMBL17068795 | 0.77 | MAPT (0.73) | SMN1; SMN2NPC1RAB9ATSHRTP53 | |
| SCHEMBL120253 | 0.77 | NPC1 (0.83) | SMN1; SMN2NPC1RAB9ATSHRCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230226193-A1 | LIPID CONJUGATES FOR THE DELIVERY OF THERAPEUTIC AGENTS | Arrowhead Pharmaceuticals, Inc. | 2023-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230226193-A1 | LIPID CONJUGATES FOR THE DELIVERY OF THERAPEUTIC AGENTS | CPT1B, MUSK, MYLK2 | SMN1; SMN2 155/4885NPC1 561/4885RAB9A 1179/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.