Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25026748 | 0.81 | TSHR (0.32) | TSHRCYP2D6 | |
| SCHEMBL30121551 | 0.81 | GBA1 (0.39) | TSHRCYP3A4CYP2D6CHRM5ADRA2C | |
| SCHEMBL29317070 | 0.79 | ACHE (0.35) | TSHR | |
| SCHEMBL25571573 | 0.79 | TSHR (0.38) | TSHR | |
| SCHEMBL30121180 | 0.79 | CHRM5 (0.35) | TSHRCHRM5ADRA2C | |
| SCHEMBL24480651 | 0.78 | NCF1 (0.38) | TSHRCHRM5ADRA2C | |
| SCHEMBL25571652 | 0.78 | CHRM5 (0.40) | CHRM5ADRA2C | |
| SCHEMBL25324905 | 0.78 | JAK2 (0.33) | CHRM5ADRA2C | |
| SCHEMBL3061830 | 0.73 | — | — | |
| SCHEMBL20881807 | 0.73 | CHRM5 (0.54) | CHRM5ADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131167-A1 | COMPOUND FOR INHIBITING AND DEGRADING IRAK4, AND PHARMACEUTICAL COMPOSITION AND PHARMACEUTICAL APPLICATION THEREOF | 海思科医药集团股份有限公司 | 2023-07-13 | — | — | WO | disclosed |