Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.43 |
| ▸ | NCF1 | P14598 | 1/20 | 0.36 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.36 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.36 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.36 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | EBP | Q15125 | 2/20 | 0.32 |
| ▸ | DHCR7 | Q9UBM7 | 2/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24480687 | 0.94 | ACHE (0.47) | ACHENCF1CARM1PRMT6PRMT1 | |
| SCHEMBL24481174 | 0.90 | ACHE (0.42) | ACHENCF1CARM1PRMT6PRMT1 | |
| SCHEMBL24480844 | 0.87 | NCF1 (0.42) | ACHENCF1KDM4ECYP1A2CYP2D6 | |
| SCHEMBL23484935 | 0.84 | ACHE (0.59) | ACHENCF1CARM1PRMT6PRMT1 | |
| SCHEMBL22703781 | 0.84 | ACHE (0.59) | ACHENCF1CARM1PRMT6PRMT1 | |
| SCHEMBL24832946 | 0.84 | ACHE (0.59) | ACHENCF1CARM1PRMT6PRMT1 | |
| SCHEMBL24481341 | 0.83 | ACHE (0.46) | ACHENCF1CARM1PRMT6PRMT1 | |
| SCHEMBL25468079 | 0.83 | ACHE (0.47) | ACHENCF1CARM1PRMT6PRMT1 | |
| SCHEMBL22703762 | 0.83 | ACHE (0.47) | ACHENCF1CARM1PRMT6PRMT1 | |
| SCHEMBL24480706 | 0.81 | NCF1 (0.44) | ACHENCF1KDM4ESIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131167-A1 | COMPOUND FOR INHIBITING AND DEGRADING IRAK4, AND PHARMACEUTICAL COMPOSITION AND PHARMACEUTICAL APPLICATION THEREOF | 海思科医药集团股份有限公司 | 2023-07-13 | — | — | WO | disclosed |