Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25924829 | 0.88 | SMN1; SMN2 (0.46) | ACHEOPRM1OPRL1KDM4EPOLB | |
| SCHEMBL24891085 | 0.82 | ACHE (0.67) | ACHEOPRM1OPRL1THRBSMN1; SMN2 | |
| SCHEMBL24838817 | 0.81 | KMT2A (0.42) | ACHEOPRM1OPRL1KMT2APOLB | |
| SCHEMBL27258576 | 0.80 | KMT2A (0.45) | ACHEKMT2AKDM4EPOLBSMN1; SMN2 | |
| SCHEMBL24480579 | 0.80 | ACHE (0.46) | ACHEOPRM1OPRL1KDM4EOPRK1 | |
| SCHEMBL24480610 | 0.80 | ACHE (0.53) | ACHEOPRM1OPRL1KDM4EOPRK1 | |
| SCHEMBL13247999 | 0.79 | ACHE (0.62) | ACHEOPRM1OPRL1KMT2AKDM4E | |
| SCHEMBL11919193 | 0.79 | KDM4E (0.50) | ACHEOPRM1OPRL1KMT2AKDM4E | |
| SCHEMBL11919254 | 0.78 | KMT2A (0.47) | ACHEOPRM1OPRL1KMT2AKDM4E | |
| SCHEMBL24480965 | 0.77 | KMT2A (0.39) | ACHEOPRM1OPRL1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131167-A1 | COMPOUND FOR INHIBITING AND DEGRADING IRAK4, AND PHARMACEUTICAL COMPOSITION AND PHARMACEUTICAL APPLICATION THEREOF | 海思科医药集团股份有限公司 | 2023-07-13 | — | — | WO | disclosed |