Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.34 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.34 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.34 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 5/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25856202 | 0.88 | ACHE (0.47) | SMN1; SMN2ACHEEPHX1KDM4EPOLB | |
| SCHEMBL25530390 | 0.81 | SMN1; SMN2 (0.61) | SMN1; SMN2DRD2SLC6A4ALDH1A1POLB | |
| SCHEMBL24480579 | 0.78 | ACHE (0.46) | SMN1; SMN2ACHEALDH1A1KDM4EOPRM1 | |
| SCHEMBL13247999 | 0.77 | ACHE (0.62) | ACHECARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL25924740 | 0.75 | SMN1; SMN2 (0.44) | SMN1; SMN2DRD2SLC6A4ALDH1A1KDM4E | |
| SCHEMBL24480610 | 0.74 | ACHE (0.53) | ACHECARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL26762491 | 0.73 | ACHE (0.52) | ACHECARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL24745065 | 0.73 | ACHE (0.42) | ACHEDRD2EPHX1EPHX2 | |
| SCHEMBL12717798 | 0.72 | CHRM5 (0.44) | ACHEDRD2 | |
| SCHEMBL10130175 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023109892-A1 | COMPOUND FOR INHIBITING OR DEGRADING BRD9, AND COMPOSITION AND PHARMACEUTICAL USE THEREOF | 海思科医药集团股份有限公司 | 2023-06-22 | — | — | WO | disclosed |