SCHEMBL25856404

SCHEMBL25856404

CC1(C)c2ccccc2Oc2ccc(-c3ccccc3C3(c4ccccc4)c4ccccc4-c4c3ccc3ccccc43)cc21

nearest known ligand 0.31

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.30
MAPT P10636 1/20 0.30
THRB P10828 1/20 0.30
PKM P14618 1/20 0.30
ALOX12 P18054 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
CYP19A1 P11511 1/20 0.30
CHRNA1 P02708 1/20 0.30
CHRNG P07510 1/20 0.30
CHRNB1 P11230 1/20 0.30
CHRNB2 P17787 1/20 0.30
SLC6A2 P23975 1/20 0.30
CHRNB4 P30926 1/20 0.30
SLC6A4 P31645 1/20 0.30
CHRNA3 P32297 1/20 0.30
CHRNA4 P43681 1/20 0.30
SLC6A3 Q01959 1/20 0.30
CHRND Q07001 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25867883 0.95 CHRNA1 (0.30) CHRNA1CHRNGCHRNB1CHRNB2SLC6A2
SCHEMBL25857379 0.93 KDM4E (0.30) KDM4EMAPTTHRBPKMALOX12
SCHEMBL25856409 0.91 GPR84 (0.32) CYP19A1
SCHEMBL25867430 0.91 CHRNA1 (0.32) CHRNA1CHRNGCHRNB1CHRNB2SLC6A2
SCHEMBL25856492 0.91 KDM4E (0.30) KDM4EMAPTTHRBPKMALOX12
SCHEMBL25856500 0.90 GPR84 (0.31)
SCHEMBL25847687 0.89 KDM4E (0.31) KDM4E
SCHEMBL25856408 0.88 GPR84 (0.32) KDM4EMAPTSMN1; SMN2
SCHEMBL25857381 0.88 DHFR (0.30)
SCHEMBL25867530 0.87

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023120714-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE 出光興産株式会社 2023-06-29 WO disclosed