Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.33 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.33 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.33 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | EBP | Q15125 | 2/20 | 0.33 |
| ▸ | DHCR7 | Q9UBM7 | 2/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24480750 | 0.87 | ACHE (0.49) | ACHEPOLBCARM1PRMT6PRMT1 | |
| SCHEMBL13247999 | 0.84 | ACHE (0.62) | ACHEPOLBKDM4ETHRBCARM1 | |
| SCHEMBL156650 | 0.84 | KDM4E (0.41) | ACHEPOLBKDM4ECARM1PRMT6 | |
| SCHEMBL25856195 | 0.83 | CHRM5 (0.53) | ACHEKDM4ETHRBCHRM5ADRA2C | |
| SCHEMBL13247682 | 0.80 | CHRM5 (0.39) | ACHEPOLBKDM4ECHRM5ADRA2C | |
| SCHEMBL842660 | 0.80 | CHRM5 (0.39) | ACHEKDM4ECHRM5ADRA2COPRM1 | |
| SCHEMBL372638 | 0.80 | CHRM5 (0.39) | ACHEKDM4ECHRM5ADRA2COPRM1 | |
| SCHEMBL372637 | 0.80 | CHRM5 (0.39) | ACHEKDM4ECHRM5ADRA2COPRM1 | |
| Hydrochloric Acid SCHEMBL19002912 | 0.79 | CHRM5 (0.38) | ACHEKDM4ECHRM5ADRA2COPRM1 | |
| Hydrochloric Acid SCHEMBL19002911 | 0.79 | CHRM5 (0.38) | ACHEKDM4ECHRM5ADRA2COPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4397661-A1 | COMPOUND FOR DEGRADATION OF BCL-2 FAMILY PROTEINS AND MEDICAL APPLICATION THEREOF | Xizang Haisco Pharmaceutical Co., Ltd. (CN) | 2024-07-10 | — | — | EP | disclosed |
| WO-2023131167-A1 | COMPOUND FOR INHIBITING AND DEGRADING IRAK4, AND PHARMACEUTICAL COMPOSITION AND PHARMACEUTICAL APPLICATION THEREOF | 海思科医药集团股份有限公司 | 2023-07-13 | — | — | WO | disclosed |