SCHEMBL25856554

SCHEMBL25856554

B[C@H]1CC(OC(C)(C)F)[C@@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O1

nearest known ligand 0.36

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
P2RY2 P41231 18/20 0.36
P2RY4 P51582 5/20 0.35
POLA1 P09884 2/20 0.35
POLB P06746 1/20 0.35
POLD1 P28340 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21308175 0.84 POLA1 (0.38) P2RY2P2RY4POLA1POLBPOLD1
SCHEMBL21308020 0.84 POLA1 (0.38) P2RY2P2RY4POLA1POLBPOLD1
SCHEMBL21307990 0.84 POLA1 (0.38) P2RY2P2RY4POLA1POLBPOLD1
SCHEMBL21307979 0.84 POLA1 (0.38) P2RY2P2RY4POLA1POLBPOLD1
SCHEMBL21308225 0.84 POLA1 (0.38) P2RY2P2RY4POLA1POLBPOLD1
SCHEMBL25856571 0.84 POLB (0.40) P2RY2P2RY4POLA1POLBPOLD1
SCHEMBL271833 0.83 P2RY2 (0.37) P2RY2P2RY4POLA1POLBPOLD1
SCHEMBL21506757 0.82 POLB (0.39) P2RY2P2RY4POLA1POLBPOLD1
SCHEMBL21555519 0.82 P2RY2 (0.37) P2RY2P2RY4POLA1POLBPOLD1
SCHEMBL21555520 0.82 P2RY2 (0.37) P2RY2P2RY4POLA1POLBPOLD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230227798-A1 MODIFIED THERMOCCOCUS POLYMERASES FIRST-CITIZENS BANK & TRUST COMPANY 2023-07-20 US disclosed