SCHEMBL25856556

SCHEMBL25856556

B[C@H]1CC(OC(C)C)[C@@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O1

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.36
POLA1 P09884 1/20 0.36
POLD1 P28340 1/20 0.36
P2RY2 P41231 17/20 0.35
P2RY4 P51582 4/20 0.35
ENTPD1 P49961 1/20 0.34
P2RY6 Q15077 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16772809 0.86 FBP1 (0.30)
SCHEMBL271833 0.85 P2RY2 (0.37) POLBPOLA1POLD1P2RY2P2RY4
SCHEMBL21506757 0.84 POLB (0.39) POLBPOLA1POLD1P2RY2P2RY4
SCHEMBL21555519 0.84 P2RY2 (0.37) POLBPOLA1POLD1P2RY2P2RY4
SCHEMBL21555520 0.84 P2RY2 (0.37) POLBPOLA1POLD1P2RY2P2RY4
SCHEMBL22002630 0.84 P2RY2 (0.37) POLBPOLA1POLD1P2RY2P2RY4
SCHEMBL272516 0.83 P2RY2 (0.36) POLBPOLA1POLD1P2RY2P2RY4
SCHEMBL271990 0.83 P2RY2 (0.37) POLBPOLA1POLD1P2RY2P2RY4
SCHEMBL21308012 0.83 POLB (0.39) POLBPOLA1POLD1P2RY2P2RY4
SCHEMBL21308184 0.83 POLB (0.39) POLBPOLA1POLD1P2RY2P2RY4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230227798-A1 MODIFIED THERMOCCOCUS POLYMERASES FIRST-CITIZENS BANK & TRUST COMPANY 2023-07-20 US disclosed