Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR2 | O15552 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.32 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.32 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.32 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.32 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.32 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.32 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2585664 | 1.00 | FFAR2 (0.35) | FFAR2HCRTR2USP30PSEN1PSEN2 | |
| SCHEMBL2587848 | 1.00 | FFAR2 (0.35) | FFAR2HCRTR2USP30PSEN1PSEN2 | |
| SCHEMBL2581025 | 0.90 | RIPK1 (0.31) | PKM | |
| SCHEMBL2581029 | 0.90 | RIPK1 (0.31) | PKM | |
| SCHEMBL2584841 | 0.90 | RIPK1 (0.31) | PKM | |
| SCHEMBL4509815 | 0.84 | FFAR2 (0.34) | FFAR2USP30PSEN1PSEN2APH1B | |
| SCHEMBL4509140 | 0.84 | FFAR2 (0.34) | FFAR2USP30PSEN1PSEN2APH1B | |
| SCHEMBL4509143 | 0.84 | FFAR2 (0.34) | FFAR2USP30PSEN1PSEN2APH1B | |
| SCHEMBL4509292 | 0.83 | FFAR2 (0.43) | FFAR2USP30PSEN1PSEN2APH1B | |
| SCHEMBL2585817 | 0.81 | RIPK1 (0.40) | FFAR2HCRTR2PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8048878-B2 | Two cyclic cinnamide compound | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2011-11-01 | — | — | US | disclosed |