Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 2/20 | 0.46 |
| ▸ | GBA1 | P04062 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | PNMT | P11086 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25833347 | 0.89 | AOC3 (0.47) | AOC3GBA1SLC6A4SLC6A2TSHR | |
| SCHEMBL25833514 | 0.84 | AOC3 (0.48) | AOC3GBA1SLC6A4SLC6A2TSHR | |
| SCHEMBL25832945 | 0.82 | SLC6A2 (0.52) | AOC3GBA1SLC6A4SLC6A2TSHR | |
| SCHEMBL25833396 | 0.79 | AOC3 (0.43) | AOC3GBA1SLC6A4SLC6A2TSHR | |
| SCHEMBL25857406 | 0.79 | AOC3 (0.43) | AOC3GBA1SLC6A4SLC6A2TSHR | |
| SCHEMBL25833427 | 0.78 | AOC3 (0.49) | AOC3GBA1SLC6A4SLC6A2TSHR | |
| SCHEMBL25833552 | 0.78 | AOC3 (0.43) | AOC3GBA1SLC6A4SLC6A2 | |
| SCHEMBL17691229 | 0.74 | PNMT (0.44) | AOC3GBA1SLC6A4SLC6A2PNMT | |
| SCHEMBL1987763 | 0.73 | PNMT (0.41) | AOC3GBA1SLC6A4SLC6A2PNMT | |
| SCHEMBL25303921 | 0.73 | AOC3 (0.47) | AOC3GBA1SLC6A4SLC6A2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4212531-A1 | AZAINDOLE DERIVATIVES AND THEIR USE AS ERK KINASE INHIBITORS | AGV Discovery (FR) | 2023-07-19 | — | — | EP | disclosed |