Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.30 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25839829 | 0.81 | PIK3R1 (0.33) | PIK3R1PIK3CA | |
| SCHEMBL30491236 | 0.78 | PAK1 (0.39) | PIK3R1PIK3CA | |
| SCHEMBL25848588 | 0.78 | PAK1 (0.39) | PIK3R1PIK3CA | |
| SCHEMBL25848577 | 0.78 | PAK1 (0.39) | PIK3R1PIK3CA | |
| SCHEMBL25303876 | 0.78 | PIK3CG (0.38) | PIK3R1PIK3CA | |
| SCHEMBL25840001 | 0.78 | PIK3R1 (0.32) | PIK3R1PIK3CA | |
| SCHEMBL30491374 | 0.78 | PIK3CG (0.38) | PIK3R1PIK3CA | |
| SCHEMBL25303880 | 0.78 | PIK3CG (0.38) | PIK3R1PIK3CA | |
| SCHEMBL25303151 | 0.77 | RIPK1 (0.35) | PIK3R1PIK3CA | |
| SCHEMBL25302877 | 0.77 | RIPK1 (0.35) | PIK3R1PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131122-A1 | FUSED RING-SUBSTITUTED SIX-MEMBERED HETEROCYCLIC COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 劲方医药科技(上海)有限公司 | 2023-07-13 | — | — | WO | disclosed |