Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 3/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | BCL2 | P10415 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | STK17B | O94768 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.32 |
| ▸ | S100A4 | P26447 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2577849 | 0.89 | AHR (0.39) | AHRCA12CA2CA9ALOX5 | |
| SCHEMBL2588284 | 0.88 | AHR (0.50) | AHRSIRT1ARCYP19A1MEN1 | |
| SCHEMBL2584754 | 0.85 | CA12 (0.40) | AHRCA12CA2CA9APP | |
| SCHEMBL2592475 | 0.78 | MKNK1 (0.36) | AHRMCL1APPKMT2ALMNA | |
| SCHEMBL2590291 | 0.72 | MAOB (0.35) | APPALOX15MEN1POLBRAB9A | |
| SCHEMBL16800942 | 0.69 | AHR (0.61) | AHRSIRT1APPARCYP19A1 | |
| SCHEMBL1842504 | 0.68 | DRD2 (0.56) | AHRARCYP19A1MEN1RAB9A | |
| SCHEMBL482685 | 0.67 | AHR (0.60) | AHRCA12CA2CA9P2RY6 | |
| SCHEMBL16455012 | 0.67 | AHR (0.65) | AHRSIRT1APPCYP19A1S100A4 | |
| SCHEMBL10448868 | 0.67 | AHR (0.74) | AHRAPPALOX15MEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011130741-A1 | COMPOUNDS FOR TREATING NEURODEGENERATIVE DISEASES | ARRAY BIOPHARMA INC. (US) | 2011-10-20 | — | — | WO | disclosed |