Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | PDE8B | O95263 | 1/20 | 0.39 |
| ▸ | EED | O75530 | 1/20 | 0.39 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.39 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.39 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.39 |
| ▸ | AEBP2 | Q6ZN18 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.37 |
| ▸ | CTSD | P07339 | 1/20 | 0.35 |
| ▸ | CTSE | P14091 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | RET | P07949 | 2/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 4/20 | 0.33 |
| ▸ | CDC7 | O00311 | 3/20 | 0.33 |
| ▸ | PDE1A | P54750 | 1/20 | 0.33 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.33 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24460764 | 0.77 | LMNA (0.52) | PKMPDE8BEEDRBBP4SUZ12 | |
| SCHEMBL21964543 | 0.75 | EED (0.43) | PKMPDE8BEEDRBBP4SUZ12 | |
| SCHEMBL25857668 | 0.72 | KDM4E (0.42) | PKMPDE8BADORA2ACTSDCTSE | |
| SCHEMBL27032676 | 0.71 | LMNA (0.78) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL31251090 | 0.70 | HDAC2 (0.44) | PKMPDE8BADORA2ACDC7PIK3CD | |
| SCHEMBL9941718 | 0.70 | DDB1 (0.40) | PKMPDE8BADORA2ARETGRM2 | |
| SCHEMBL30600060 | 0.69 | LMNA (0.75) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL23284480 | 0.68 | GRM2 (0.45) | PKMLMNAGRM2 | |
| SCHEMBL13412131 | 0.68 | LRRK2 (0.41) | PIK3CACDC7PDE1APDE1BPDE1C | |
| SCHEMBL16593759 | 0.68 | LRRK2 (0.41) | PKMPDE8BLMNAPIK3CACDC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107723-A2 | METHODS FOR TREATING NEUROLOGICAL DISORDERS | PROTHENA BIOSCIENCES LIMITED (IE) | 2023-06-15 | — | — | WO | disclosed |